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Diagnosis of Inherited Platelet Disorders on a Blood Smear [PDF]

Journal of Clinical Medicine, 2020
Inherited platelet disorders (IPDs) are rare diseases featured by low platelet count and defective platelet function. Patients have variable bleeding diathesis and sometimes additional features that can be congenital or acquired. Identification of an IPD is desirable to avoid misdiagnosis of immune thrombocytopenia and the use of improper treatments ...
Carlo Zaninetti, Andreas Greinacher
openaire   +4 more sources

Platelet-Like Bodies in Urine in Some Blood Disorders [PDF]

Thrombosis and Haemostasis, 1977
We had reported that it is always observed a small body resembling a platelet in urine of normal and various sick persons and the small body is a platelet itself or a ruin of platelet (Lancet, 1, 1339, 1975., N. Engl. J. Med., 293, 44, 1975., Nihon Univ. J. Med., 17, 117, 1975., Japan. J. Clin. Hemat., 17, 632, 1976., Jap. J. Urol., 67, 903, 1976.). We
N. Kōno, T.P. Chen, N. Suzawa, T. Mizokami   +3 more
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Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders [PDF]

Journal of Thrombosis and Haemostasis, 2017
Essentials There are many hereditary platelet disorders (HPD) but diagnosing these is challenging. We provide a method to diagnose several HPDs using standard blood smears requiring < 100 µL blood. By this approach, the underlying cause of HPD was characterized in ~25-30% of referred individuals.
Greinacher, Andreas, PECCI, ALESSANDRO, Kunishima, Shinji, Althaus, Karina, Nurden, Paquita, BALDUINI, CARLO, Bakchoul, Tamam   +6 more
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Blood platelet research in autism spectrum disorders: In search of biomarkers [PDF]

Research and Practice in Thrombosis and Haemostasis, 2019
Autism spectrum disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder that is caused by gene-environment interactions. To improve its diagnosis and treatment, numerous efforts have been undertaken to identify reliable biomarkers for autism.
Padmakumar, Manisha, Van Raes, Eveline, Van Geet, Chris, Freson, Kathleen   +3 more
openaire   +4 more sources

Features of Morphometric Changes in Platelets and Red Blood Cells in Women with Various Forms of Hypertensive Disorders in the Third Trimester of Pregnancy

Acta Biomedica Scientifica, 2020
Background. Arterial hypertension during pregnancy is accompanied by pronounced changes in microcirculation and hemostasis in the system, the state of which is largely determined by the structural and functional properties of red blood cells and ...
R. I. Sadov, T. O. Baev, I. A. Panova, S. V. Nazarov, G. N. Kuzmenko   +4 more
doaj   +2 more sources

Assessment of platelet indices, beta-thromboglobulin and platelet factor IV in platelet concentrate at University of Ilorin Teaching Hospital, Nigeria [PDF]

Scientific Reports
Platelet concentrate transfusion remains a major therapeutic care for patient with hematological disorders. However, optimal therapeutic effect has been a major challenge.
Luqman Olayinka Olatunbosun, Musa Abidemi Muhibi, Olusegun Taiwo Oke, Samuel Abiola Babatunde, Abdulwaheed Adewale Ademosun, Fatai Dayo Olalere, Emmanuel Oladipo Sanni, Mutiat Aina Kareem, Raufu Taiwo Azeez, Fatai Kayode Adebayo, Mubarak Abubakar Yusuf, Roheemot Damilare Uthman, Aasiyah Oyinkansola Idris   +12 more
doaj   +2 more sources

Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance

Медицинская иммунология, 2022
Blood platelets are the central players in thrombosis and blood coagulation. Moreover, they also exhibit immunoregulatory properties and bridge hemostasis and immunity.
O. V. Pavlov, S. V. Chepanov, A. V. Selutin, S. A. Selkov   +3 more
doaj   +1 more source

Dialysis-related thrombocytopenia: a case report

Brazilian Journal of Nephrology, 2021
Thrombocytopenia is frequently observed in hemodialysis patients, and its correct investigation and control remain a challenge. It is estimated that during the hemodialysis session there is a drop of up to 15% in the platelet count, with recovery after ...
Irene Faria Duayer, Maria Júlia Correia Lima Nepomuceno Araújo, Camila Hitomi Nihei, Maria Alice Fernandes Barcelos, Osni Braga, Zita Maria Leme Britto, Rosilene Mota Elias   +6 more
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Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. [PDF]

PLoS ONE, 2015
Recent work has indicated that platelets, which are anucleate blood cells, significantly contribute to inflammatory disorders. Importantly, platelets also likely contribute to various inflammatory secondary disorders that are increasingly associated with
Michelle Kiebala, Meera V Singh, Michael S Piepenbrink, Xing Qiu, James J Kobie, Sanjay B Maggirwar   +5 more
doaj   +1 more source

Elevated Monocyte Levels Maybe a Common Peripheral Inflammatory Marker in Specific Learning Disorders and Attention Deficit/Hyperactivity Disorder

Psychiatry and Behavioral Sciences, 2022
Aim: the primary aim of this study was to determine whether the neutrophil / lymphocyte ratio, mean platelet volume, monocyte/ lymphocyte ratio and distribution width of red blood cells are different in children with specific learning disorders compared ...
Cigdem Yektas, Ali Evren Tufan, Onder Kilicaslan, Merve Yazici, Sumeyra Elif Kaplan Karakaya, Enes Sarigedik   +5 more
doaj   +1 more source