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Blood platelet research in autism spectrum disorders: In search of biomarkers [PDF]
Autism spectrum disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder that is caused by gene‐environment interactions. To improve its diagnosis and treatment, numerous efforts have been undertaken to identify reliable biomarkers for ...
Manisha Padmakumar+3 more
doaj +6 more sources
Diagnosis of Inherited Platelet Disorders on a Blood Smear [PDF]
Inherited platelet disorders (IPDs) are rare diseases featured by low platelet count and defective platelet function. Patients have variable bleeding diathesis and sometimes additional features that can be congenital or acquired. Identification of an IPD
Carlo Zaninetti, Andreas Greinacher
semanticscholar +6 more sources
Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders [PDF]
Essentials There are many hereditary platelet disorders (HPD) but diagnosing these is challenging. We provide a method to diagnose several HPDs using standard blood smears requiring < 100 µL blood. By this approach, the underlying cause of HPD was characterized in ~25-30% of referred individuals.
Andreas Greinacher+6 more
semanticscholar +6 more sources
Use of whole blood platelet lumi‐aggregometry to optimize anti‐platelet therapy in patients with chronic myeloproliferative disorders [PDF]
AbstractTwenty‐seven patients with chronic myeloproliferative disorders and in vitro evidence of platelet hyperactivity on whole blood platelet lumi‐aggregometry were commenced on anti‐platelet therapy comprising aspirin, clopidogrel, and/or odorless garlic and the studies were repeated to assess the efficacy of the therapeutic agent(s).
A. Manoharan+2 more
semanticscholar +4 more sources
Platelet-Like Bodies in Urine in Some Blood Disorders [PDF]
We had reported that it is always observed a small body resembling a platelet in urine of normal and various sick persons and the small body is a platelet itself or a ruin of platelet (Lancet, 1, 1339, 1975., N. Engl. J. Med., 293, 44, 1975., Nihon Univ. J. Med., 17, 117, 1975., Japan. J. Clin. Hemat., 17, 632, 1976., Jap. J. Urol., 67, 903, 1976.). We
Natsu Kono+3 more
openalex +2 more sources
Considerations on Blood Platelets: A Neuron’s Mirror for Mood Disorders?
This work aims to be a reflection concerning a remarkable similarity between platelet and neuron. Through a series of experimental tests which have affected the fatty acid composition of the membrane of platelets, it was possible to provide a contribution to the scientific literature, which had already reported strong similarities between platelet and ...
Massimo Cocchi+2 more
openalex +5 more sources
Not ...
Benedetta Izzi, José J. Fuster
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Platelet Satellitism in a Patient with Underlying Infection, Immune Thrombocytopenic Purpura (ITP) and Multiple Sclerosis [PDF]
Platelet satellitism (PS) is an in vitro phenomenon of platelets adhering around white blood cells, especially in blood samples anticoagulated with K3EDTA.
Athanasios Liaskas+4 more
doaj +2 more sources
Background. According to modern knowledge, macrophages and platelets support the growth and development of endometrioid heterotopia, thereby maintaining its survival under unsuitable conditions.Objectives. To carry out a comparative analysis of blood tests with a particular focus on platelet and monocyte count in patients suffering from various forms ...
Р. В. Украинец, Yu. S. Korneva
openalex +5 more sources
Inherited platelet disorders (IPDs) are rare diseases characterized by reduced blood platelet counts and/or impaired platelet function. Recognizing IPDs is advisable but often challenging. The diagnostic tools include clinical evaluation, platelet function tests, and molecular analyses. Demonstration of a pathogenic genetic variant confirms IPDs.
Carlo Zaninetti+7 more
openalex +4 more sources