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血小板異常には量的異常と質的異常がある.前者では血小板減少症が大半を占め,血小板数が大略10万以下の時に診断する.原因は血小板の骨髄での産生不全,血小板の破壊や消費亢進,血小板の体内でのプール異常によるものなどがある.血小板増加症には腫瘍性のものと二次性のものがある.質的異常は血小板機能異常症であり,血小板数が正常なのに出血時間の延長を認める.先天性のものより後天性のものが頻度が高く,症状は軽い.
渡辺 清明
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Thrombosis and bleeding in myeloproliferative disorders: identification of at‐risk patients with whole blood platelet aggregation studies [PDF]
A. Manoharan+5 more
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Mean Platelet Volume and Immature Platelet Fraction in Autoimmune Disorders
Mean platelet volume (MPV), measured using automated blood analysers, has been appraised as a potential biomarker in cardiovascular disease, diabetes mellitus, and cancer.
Deonilson Schmoeller+4 more
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Evaluation of a whole blood remote platelet function test for the diagnosis of mild bleeding disorders [PDF]
Natalia Dovlatova+7 more
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Red Blood Cell and Platelet Indices: A Potential Biomarker for Panic Disorder [PDF]
Roshan Bhad
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Whole Blood Serotonin Levels and Platelet 5-HT2A Binding in Autism Spectrum Disorder [PDF]
E. A. Aaron+10 more
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Diagnostic workup of inherited platelet disorders
Inherited platelet disorders (IPDs) can cause mucocutaneous bleeding due to impaired primary hemostatic function of platelets, thrombocytopenia, or both.
Bohyun Kim
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Screening and diagnosis of inherited platelet disorders
Inherited platelet disorders are important conditions that often manifest with bleeding. These disorders have heterogeneous underlying pathologies.
Alex Bourguignon, S. Tasneem, C. Hayward
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Platelets are the “guardians” of the blood circulatory system. At sites of vessel injury, they ensure hemostasis and promote immunity and vessel repair. However, their uncontrolled activation is one of the main drivers of thrombosis.
Anisa Degjoni+3 more
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Dialysis-related thrombocytopenia: a case report
Thrombocytopenia is frequently observed in hemodialysis patients, and its correct investigation and control remain a challenge. It is estimated that during the hemodialysis session there is a drop of up to 15% in the platelet count, with recovery after ...
Irene Faria Duayer+6 more
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