Results 101 to 110 of about 4,705,585 (363)
PLATELET TURNOVER AND ATHEROTHROMBOSIS
Атеротромбоз, 2017 Platelets play an important role in initiating atherothrombosis, i.e. the formation of blood clots inside a blood vessel at areas of atherosclerotic vascular injury.
A. V. MAZUROV
doaj +1 more source
Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide. [PDF]
PLoS ONE, 2011 BACKGROUND: Pro-coagulant membrane microvesicles (MV) derived from platelets and leukocytes are shed into the circulation following receptor-mediated activation, cell-cell interaction, and apoptosis. Platelets are sentinel markers of toll-like receptor 4
Jing Xiong +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji +11 more
wiley +1 more source
Shiga toxin and lipopolysaccharide induce platelet-leukocyte aggregates and tissue factor release, a thrombotic mechanism in hemolytic uremic syndrome. [PDF]
PLoS ONE, 2009 BACKGROUND:Aggregates formed between leukocytes and platelets in the circulation lead to release of tissue factor (TF)-bearing microparticles contributing to a prothrombotic state.
Anne-lie Ståhl +4 more
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Blood platelets contain tumor-derived RNA biomarkers.
Blood, 2011 Diagnostic platforms providing biomarkers that are highly predictive for diagnosing, monitoring, and stratifying cancer patients are key instruments in the development of personalized medicine.
R. J. Nilsson +12 more
semanticscholar +1 more source
Advanced Biology, EarlyView.The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo +5 more
wiley +1 more source
Therapeutic use of red blood cells and platelets derived from human cord blood stem cells
Stem Cells Translational Medicine, 2021 Red blood cells (RBCs) and platelets derived from stem cells are possible solutions to the increasing demand for blood transfusion. Based on the availability of stem cells, their relatively defined differentiation mechanisms, and the massive exploration ...
Xiaoyan Xie +4 more
doaj +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Role of platelets and platelet receptors in cancer metastasis
Journal of Hematology & Oncology, 2018 The interaction of tumor cells with platelets is a prerequisite for successful hematogenous metastatic dissemination. Upon tumor cell arrival in the blood, tumor cells immediately activate platelets to form a permissive microenvironment.
M. Schlesinger
semanticscholar +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Advanced Biology, EarlyView.Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source