Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]
, 2017 NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina +8 more
core +1 more source
Engineering Highly Cellularized Living Materials via Mechanical Agitation
Advanced Functional Materials, EarlyView.A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani +9 more
wiley +1 more source
DIMINISHED BLOOD PLATELETS AND MARROW INSUFFICIENCY [PDF]
, 1917 GEORGE R. MINOT
openalex +3 more sources
Isolation of Human Platelets (Thrombocytes)
The Scientific World Journal, 2002 Platelets from human blood can be isolated in high yield by centrifugation of whole blood over an iodixanol density barrier of 1.063 g/ml. The separation from all of the blood cells (which form a pellet) is based on the slower sedimentation velocity of ...
John Graham
doaj +1 more source
Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]
, 2008 Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon +8 more
core +1 more source
Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass [PDF]
, 1999 Objectives: The investigation centers on whether there is a reperfusion-induced specific cardiac inflammatory reaction after bypass surgery. Background: Cardiopulmonary bypass (CPB) leads to systemic inflammation.
Becker, Bernhard F. +5 more
core +1 more source
Advanced Functional Materials, EarlyView.Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka +3 more
wiley +1 more source
Spatial confinement alters morphology, spreading dynamics, and mechanics of adherent platelets
Biophysical ReportsPlatelets are small blood cells involved in hemostasis and wound healing. After activation, platelets interact with their surrounding environment and respond to biochemical and mechanical stimuli by mechanosensitive and haptotactic mechanisms.
Johanna G. Rodríguez +4 more
doaj +1 more source
Adhesion and Activation of Blood Platelets on Laser-Structured Surfaces of Biomedical Metal Alloys. [PDF]
J Funct Biomater, 2023 Kamińska M +5 more
europepmc +1 more source
Using Platelet-Rich Plasma to Reverse the Effects of Tendinopathy and Prevent Tendon Re-rupture after Surgery in Athletes: The Search for a Standardized Protocol [PDF]
, 2016 30-50% of all lesions amateur and professional sports players will experience during activity are related to the tendon. Moreover, the incidence of tendinopathy, a precursor to tendon rupture, is much higher in both of these groups due to excessive ...
Patel, Shiv
core +1 more source