Results 111 to 120 of about 410,702 (329)

Isolation of Human Platelets (Thrombocytes)

The Scientific World Journal, 2002
Platelets from human blood can be isolated in high yield by centrifugation of whole blood over an iodixanol density barrier of 1.063 g/ml. The separation from all of the blood cells (which form a pellet) is based on the slower sedimentation velocity of ...
John Graham
doaj   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

Morphological substrate of platelet hemostasis damage in patients with type 2 diabetes mellitus and hypertension.

Морфологія, 2015
Background. Disorders of hemostasis in patients with arterial hypertension and diabetes mellitus type 2 are complex: growing aggregative activity of platelets and red blood cells, activation and degranulation of platelet antiaggregatory potential ...
N. O. Pertseva
doaj   +1 more source

Force generation in human blood platelets by filamentous actomyosin structures. [PDF]

Biophys J, 2023
Zelená A, Blumberg J, Probst D, Gerasimaitė R, Lukinavičius G, Schwarz US, Köster S.   +6 more
europepmc   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

DIMINISHED BLOOD PLATELETS AND MARROW INSUFFICIENCY [PDF]

, 1917
GEORGE R. MINOT
openalex   +3 more sources

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

Ultrastructural platelet disorders in patients with type 2 diabetes mellitus and hypertension.

Морфологія, 2016
Background. Disorders of hemostasis in patients with arterial hypertension and diabetes mellitus type 2 are complex: growing aggregative activity of platelets and red blood cells, activation and degranulation of platelet antiaggregatory potential ...
N. O. Pertseva
doaj   +1 more source

Adhesion and Activation of Blood Platelets on Laser-Structured Surfaces of Biomedical Metal Alloys. [PDF]

J Funct Biomater, 2023
Kamińska M, Jastrzębska A, Walkowiak-Przybyło M, Walczyńska M, Komorowski P, Walkowiak B.   +5 more
europepmc   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

Advanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao, Qianqian Bai, Yifei Zhao, Xingyi Dai, Yuan Liu, Xiao Han, Jianhua Hao   +6 more
wiley   +1 more source