Results 111 to 120 of about 4,705,585 (363)

Acoustophoretic purification of platelets: feasibility and impact on platelet activation and function

open access: yesPlatelets, 2019
Purity, limited platelet activation, and preservation of platelet function are important stakes of preparation of platelet concentrates (PC) for clinical use.
Pierre Bohec   +6 more
doaj   +1 more source

An investigation of the antiplatelet effects of succinobucol (AGI-1067) [PDF]

open access: yes, 2016
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant ...
Gnanadesika, Sukanya   +3 more
core   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

open access: yesAdvanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu   +12 more
wiley   +1 more source

In vitro-derived platelets: the challenges we will have to face to assess quality and safety

open access: yesPlatelets, 2020
Platelet transfusions are given to patients in hospital who have a low blood platelet count (thrombocytopenia) either because of major bleeding (following trauma or surgery) or because the bone marrow production of platelets is impaired often due to ...
S. Mookerjee   +3 more
doaj   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

open access: yesAdvanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran   +5 more
wiley   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

An acoustofluidic device for the automated separation of platelet-reduced plasma from whole blood

open access: yesMicrosystems & Nanoengineering
Separating plasma from whole blood is an important sample processing technique required for fundamental biomedical research, medical diagnostics, and therapeutic applications.
Zhehan Ma   +11 more
doaj   +1 more source

Thrombin-induced cytoskeleton dynamics in spread human platelets observed with fast scanning ion conductance microscopy

open access: yesScientific Reports, 2017
Platelets are small anucleate blood cells involved in haemostasis. Platelet activation, caused by agonists such as thrombin or by contact with the extracellular matrix, leads to platelet adhesion, aggregation, and coagulation. Activated platelets undergo
Jan Seifert   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy