Results 131 to 140 of about 4,844,363 (388)
Advanced Healthcare Materials, EarlyView.This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin +14 more
wiley +1 more source
Spatial confinement alters morphology, spreading dynamics, and mechanics of adherent platelets
Biophysical ReportsPlatelets are small blood cells involved in hemostasis and wound healing. After activation, platelets interact with their surrounding environment and respond to biochemical and mechanical stimuli by mechanosensitive and haptotactic mechanisms.
Johanna G. Rodríguez +4 more
doaj +1 more source
Behaviour of the von Willebrand Factor in Blood Flow [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +3 more
core
Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices
Advanced Healthcare Materials, EarlyView.Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco +4 more
wiley +1 more source
Adhesion and Activation of Blood Platelets on Laser-Structured Surfaces of Biomedical Metal Alloys. [PDF]
J Funct Biomater, 2023 Kamińska M +5 more
europepmc +1 more source
The role of platelets in mediating a response to human influenza infection
Nature Communications, 2019 Influenza infection increases the incidence of myocardial infarction but the reason is unknown. Platelets mediate vascular occlusion through thrombotic functions but are also recognized to have immunomodulatory activity.
Milka Koupenova +12 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu +3 more
wiley +1 more source
How different are blood platelets from women or men, and young or elderly people? [PDF]
Haematologica, 2023 De Gaetano G, Bonaccio M, Cerletti C.
europepmc +1 more source
Platelets, Thrombo-Inflammation, and Cancer: Collaborating With the Enemy
Frontiers in Immunology, 2019 Platelets are small anucleate cells present in the blood stream, their typical role in primary hemostasis has been well-described. However, new evidence suggests that they have critically important roles in cancer progression and inflammation.
Ana-Luisa Palacios-Acedo +5 more
semanticscholar +1 more source
Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
Advanced Healthcare Materials, EarlyView.3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar +7 more
wiley +1 more source