This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin +14 more
wiley +1 more source
Interactions of fentanyl with blood platelets and plasma proteins: platelet sensitivity to prasugrel metabolite is not affected by fentanyl under in vitro conditions. [PDF]
Bednarek R +3 more
europepmc +1 more source
The association of adrenaline and noradrenaline with blood platelets [PDF]
H. Weil‐Malherbe, A. D. Bone
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A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben +8 more
wiley +1 more source
Transcriptomic landscape of blood platelets in healthy donors. [PDF]
Supernat A +12 more
europepmc +1 more source
The Examination of the Tissues and Some Observations on the Blood Platelets of Rabbits at Intervals of Five Minutes, and Later, after Intravenous Inoculations of Staphylococcus aureus and Indian Ink [PDF]
Leonard S. Dudgeon, H. K. Goadby
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Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco +4 more
wiley +1 more source
Pseudothrombocytopenia and other conditions associated with spuriously low platelet counts
Accurate measurements of the platelet count are necessary to diagnose thrombocytosis or thrombocytopenia correctly, gauge the severity of the clinical risk and identify the most appropriate therapeutic intervention. Despite increased diagnostic accuracy
Marco Cattaneo
doaj +1 more source
Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons. [PDF]
Want A +4 more
europepmc +1 more source
A consideration of the reduction of blood platelets in purpura [PDF]
ALFRED F. HESS
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