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K, BULUK, T, JANUSZKO, M, MALOFIEJEW
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Thrombosis Research, 2012
Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet activation and aggregation and the formation a haemostatic plug ...
Katleen, Broos +4 more
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Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet activation and aggregation and the formation a haemostatic plug ...
Katleen, Broos +4 more
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Blood Platelets and Platelet Transfusions
Archives of Internal Medicine, 1961The application of quantitative biological and biochemical methods to the study of the blood platelets has led to revolutionary developments in our understanding of these elusive structures. 1 Until recently platelets were often regarded as non-cellular in nature, although it has long been known that they are of cellular origin.
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Archives of Internal Medicine, 1930
Numerous methods for counting blood platelets have appeared since Schultze's 1 original description in 1865 of these "granular formations" as microscopic cellular constituents of normal blood. Hittmair 2 in his recent review of the literature referred to twenty new methods that had appeared within the previous ten years.
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Numerous methods for counting blood platelets have appeared since Schultze's 1 original description in 1865 of these "granular formations" as microscopic cellular constituents of normal blood. Hittmair 2 in his recent review of the literature referred to twenty new methods that had appeared within the previous ten years.
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Whole Blood Platelet Aggregometry
2017Light transmittance aggregometry is the historical reference method for platelet function testing and continues to be used extensively. Whole blood impedance lumiaggregometry represents an updated methodology that provides for simplified specimen management, an assay milieu that replicates in vivo platelet activation conditions, improved ...
George A, Fritsma, David L, McGlasson
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Journal of Cardiovascular Pharmacology, 1984
The intravascular adhesion and aggregation of platelets initiate hemostasis and arterial thrombosis. In vitro, platelet aggregation is induced by many different agents; which of these is responsible for aggregation in vivo is now under investigation.
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The intravascular adhesion and aggregation of platelets initiate hemostasis and arterial thrombosis. In vitro, platelet aggregation is induced by many different agents; which of these is responsible for aggregation in vivo is now under investigation.
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Blood Platelet Inventory Management
2017This paper illustrates how MDP or Stochastic Dynamic Programming (SDP) can be used in practice for blood management at blood banks; both to set regular production quantities for perishable blood products (platelets) and how to do so in irregular periods (as holidays). The state space is too large to solve most practical problems using SDP. Nevertheless
Haijema, R. +2 more
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Bulletin de l'Academie nationale de medecine, 2014
Studies of inherited platelet disorders have led to major advances in our knowledge of platelet physiology, thus permitting the development of antiplatelet agents that are now widely used to treat vascular diseases. New therapeutic strategies have also resulted from a better understanding of megakaryocytopoiesis, notably including the use of ...
Jacques, Caen, Sylvia, Bellucci
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Studies of inherited platelet disorders have led to major advances in our knowledge of platelet physiology, thus permitting the development of antiplatelet agents that are now widely used to treat vascular diseases. New therapeutic strategies have also resulted from a better understanding of megakaryocytopoiesis, notably including the use of ...
Jacques, Caen, Sylvia, Bellucci
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Antigenicity of Blood Platelets
1969The first knowledge of the antigenicity of platelets dates from the beginning of this century (Marino, 4905). The authors studied at first the antigenicity in heterorelationship in animals and heteroantibodies, obtained by immunization, were used frequently to provoke experimental thrombopenic purpura. Cole (1907) was the first to prepare a heteroserum
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