Advanced Science, EarlyView.Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin +14 more
wiley +1 more source
The Effects of Caffeine on Blood Platelets and the Cardiovascular System through Adenosine Receptors. [PDF]
Int J Mol SciMarcinek K, Luzak B, Rozalski M.
europepmc +1 more source
Content of RANTES, IL-8 and MIP-1β chemokines in platelet lysates obtained from donor blood [PDF]
В. В. Шуплецова +9 more
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In vitro effect of the herbicide glyphosate on human blood platelet aggregation and coagulation [PDF]
, 2010 Teresinha de Jesus Carvalho Neiva +7 more
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Advanced Science, EarlyView.This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng +15 more
wiley +1 more source
On-site Prothrombin Time, Activated Partial Thromboplastin Time, and Platelet Count A Comparison between Whole Blood and Laboratory Assays with Coagulation Factor Analysis in Patients Presenting for Cardiac Surgery [PDF]
, 1994 George J. Despotis +6 more
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Advanced Science, EarlyView.This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao +5 more
wiley +1 more source
New light on changes in the number and function of blood platelets stimulated by cocoa and its products. [PDF]
Front PharmacolOlas B.
europepmc +1 more source
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency [PDF]
, 1984 HJ Weiss +3 more
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Advanced Science, EarlyView.A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi +8 more
wiley +1 more source