Effects of inorganic ions and of plasma proteins on the aggregation of blood platelets by adenosine diphosphate [PDF]
G. V. R. Born, Michael Cross
openalex +1 more source
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
The Effects of Caffeine on Blood Platelets and the Cardiovascular System through Adenosine Receptors. [PDF]
Marcinek K, Luzak B, Rozalski M.
europepmc +1 more source
The influence of salicylate on platelets and whole blood adenine nucleotides [PDF]
D. T. P. Davies +2 more
openalex +1 more source
The Enumeration of Blood‐Platelets
A. E. Russell, T. G. Brodie
openaire +3 more sources
Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao +13 more
wiley +1 more source
Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong +16 more
wiley +1 more source
New light on changes in the number and function of blood platelets stimulated by cocoa and its products. [PDF]
Olas B.
europepmc +1 more source
Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani +6 more
wiley +1 more source
Immunological Signatures for Early Detection of Human Head and Neck Squamous Cell Carcinoma through RNA Transcriptome Analysis of Blood Platelets. [PDF]
Gill JS +10 more
europepmc +1 more source

