Presence and activity of Fibrinogen like protein 2 in platelets.
PLoS ONE, 2023 BackgroundFibrinogen-like protein 2 (FGL2) is a serine protease capable of converting prothrombin into thrombin (i.e., prothrombinase-like activity) while bypassing the classic coagulation cascade.
Izhack Cherny +5 more
doaj +1 more source
Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]
, 2016 Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle +4 more
core +2 more sources
Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
, 2002 Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E. +3 more
core +1 more source
Perbedaan Hitung Jumlah Trombosit Menggunakan Darah Vena dan Darah Kapiler
Journal of Health (JOH), 2016 Background: Platelets play a role in hemostasis which is the body's mechanisms to prevent and stop the bleeding. Platelets participate in the effort to close the wound, so that the body does not experience a loss of blood and protected from foreign cells.
Hieronymus Rayi Prasetya +2 more
doaj +1 more source
Assessment of neonatal, cord, and adult platelet granule trafficking and secretion
Platelets, 2020 Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis.
Anh T. P. Ngo +12 more
doaj +1 more source
A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device [PDF]
, 2019 Background and objectives: Several sources of haematopoietic stem cells have been used for static culture of megakaryocytes to produce platelets in vitro.
Baruch, Dominique +5 more
core +1 more source
Platelets, 2022 Citrate is the recommended anticoagulant for studies on plasma extracellular vesicles (EVs). Because citrate incompletely blocks platelet activation and the release of platelet-derived EVs, we compared EDTA and citrate in that regard.
Naomi C. Buntsma +5 more
doaj +1 more source
Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]
, 2003 Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike +9 more
core +1 more source
Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]
, 2017 Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S +3 more
core +2 more sources
Glucose metabolism and metabolic flexibility in blood platelets
Journal of Thrombosis and Haemostasis, 2018 Essentials The metabolic integration processes required for platelet activation are unclear. The metabolic plasticity of human platelets were investigated.
Miriayi Aibibula +2 more
semanticscholar +1 more source