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In vitro Generation of Megakaryocytes and Platelets
Frontiers in Cell and Developmental Biology, 2021 Platelets, the tiny anucleate cells responsible for stopping bleeding through thrombosis, are derived from hematopoietic stem cells through a series of differentiation steps.
Huicong Liu +3 more
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Hospital Pharmacology, 2016 Introduction: Pseudo thrombocytopenia (PTP) is a phenomenon of falsely low platelet counts obtained on Hematology Analyzers (HA) due to in vitro platelet clumping in the presence of anticoagulants.
Nikolić Ljubinka I. +2 more
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Effects of the interactions between platelets with other cells in tumor growth and progression
Frontiers in Immunology, 2023 It has been confirmed that platelets play a key role in tumorigenesis. Tumor-activated platelets can recruit blood cells and immune cells to migrate, establish an inflammatory tumor microenvironment at the sites of primary and metastatic tumors.
Yaxin Li +5 more
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Adenosine and blood platelets [PDF]
Purinergic Signalling, 2011 Adenosine is an important regulatory metabolite and an inhibitor of platelet activation. Adenosine released from different cells or generated through the activity of cell-surface ectoenzymes exerts its effects through the binding of four different G-protein-coupled adenosine receptors.
Hillary A, Johnston-Cox, Katya, Ravid
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2021 Although platelets and the coagulation factors are components of the blood system, they become part of and contribute to the tumor microenvironment (TME) not only within a solid tumor mass, but also within a hematogenous micrometastasis on its way ...
Wolfgang M. J. Obermann +2 more
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JTCVS Open, 2023 Objective: Dimethylsulfoxide-cryopreserved platelets are being evaluated for treatment of acute hemorrhage in patients with thrombocytopenia or platelet dysfunction when liquid stored platelets are unavailable.
Glenn Whitman, MD +6 more
doaj +1 more source
Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets [PDF]
Molecules, 2018 Angela Dziedzic +2 more
exaly +2 more sources
Presence and activity of Fibrinogen like protein 2 in platelets.
PLoS ONE, 2023 BackgroundFibrinogen-like protein 2 (FGL2) is a serine protease capable of converting prothrombin into thrombin (i.e., prothrombinase-like activity) while bypassing the classic coagulation cascade.
Izhack Cherny +5 more
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Perbedaan Hitung Jumlah Trombosit Menggunakan Darah Vena dan Darah Kapiler
Journal of Health (JOH), 2016 Background: Platelets play a role in hemostasis which is the body's mechanisms to prevent and stop the bleeding. Platelets participate in the effort to close the wound, so that the body does not experience a loss of blood and protected from foreign cells.
Hieronymus Rayi Prasetya +2 more
doaj +1 more source
Assessment of neonatal, cord, and adult platelet granule trafficking and secretion
Platelets, 2020 Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis.
Anh T. P. Ngo +12 more
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