ABO Groups in Blood Platelets [PDF]
Nature, 1954 IT has been found that suspensions of blood platelets in normal saline are agglutinated by A- B- and O-sera, just as these sera agglutinate red blood cells of the corresponding blood group. It is thus possible to establish four blood groups for the blood platelets, similar to the blood groups in erythrocytes.
J, GUREVITCH, D, NELKEN
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Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]
, 2008 Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW +18 more
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Blood, 1947 Abstract 1. The rate of utilization of blood platelets in radiated, thrombopenic cats has been measured directly. Thrombopenic animals, incapable of significant platelet regeneration, were cross circulated via carotid to carotid anastomoses with normal animals.
JOHN S. LAWRENCE, WILLIAM N. VALENTINE
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Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction [PDF]
, 2018 The MEK inhibitors cobimetinib and trametinib are used in combination with BRAF inhibitors to treat metastatic melanoma but increase rates of hemorrhage relative to BRAF inhibitors alone.
Bye, Alex P. +6 more
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Leucoreduction of blood components. an effective way to increase blood safety? [PDF]
, 2015 Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria +6 more
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Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization,secondary mediators, and Rac [PDF]
, 2010 The C-type lectin-like receptor 2 (CLEC-2)activates platelets through Src and Syk tyrosine kinases via a single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM).Here, we demonstrate using sucrose gradient ...
Alice Y. Pollitt +44 more
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Relationship between the Increased Haemostatic Properties of Blood Platelets and Oxidative Stress Level in Multiple Sclerosis Patients with the Secondary Progressive Stage [PDF]
, 2015 Multiple sclerosis (MS) is the autoimmune disease of the central nervous system with complex pathogenesis, different clinical courses and recurrent neurological relapses and/or progression. Despite various scientific papers that focused on early stage of
Bijak, Michal +5 more
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Origin of Blood Platelets [PDF]
Nature, 1955 THE conclusion of J. H. Wright1 that blood platelets are detached portions of the cytoplasm of megakaryocytes has been supported by much circumstantial evidence, and is generally accepted2, although unequivocal direct evidence is lacking.
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An investigation of the antiplatelet effects of succinobucol (AGI-1067) [PDF]
, 2016 Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant ...
Gnanadesika, Sukanya +3 more
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Platelet Biochemistry and Morphology after Cryopreservation [PDF]
, 2020 Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle +2 more
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