Results 31 to 40 of about 484,220 (201)
Platelets, 2020 The main pathological process associated to increased intestinal permeability is the translocation of toxic products, predominantly endotoxins/lipopolysaccharide (LPS), from the intestinal tract into the microcirculation.
Mercedes Lopez, Goetz Nowak
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A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device [PDF]
, 2019 Background and objectives: Several sources of haematopoietic stem cells have been used for static culture of megakaryocytes to produce platelets in vitro.
Baruch, Dominique +5 more
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Blood platelet kinetics and platelet transfusion [PDF]
Journal of Clinical Investigation, 2013 The discovery of citrate anticoagulant in the 1920s and the development of plastic packs for blood collection in the 1960s laid the groundwork for platelet transfusion therapy on a scale not previously possible. A major limitation, however, was the finding that platelet concentrates prepared from blood anticoagulated with citrate were unsuitable for ...
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The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation [PDF]
, 2016 A dynamic, properly organised actin cytoskeleton is critical for the production and haemostatic function of platelets. The Wiskott Aldrich Syndrome protein (WASp) and Actin-Related Proteins 2 & 3 Complex (Arp2/3 complex) are critical mediators of ...
Bem, Danai +5 more
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Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]
, 2019 We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina +9 more
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THE HISTOGENESIS OF BLOOD PLATELETS [PDF]
Journal of Experimental Medicine, 1913 1. Under normal circumstances blood platelets are largely derived from the megakaryocyte of the blood-forming organs. 2. The transitional leucocyte, representing a persistent form of the embryonic premegakaryocyte, is a circulating homologue of the megakaryocyte and probably plays some part in normal platelet formation. 3.
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BLOOD-PLATELETS AND TUBERCULOSIS [PDF]
Archives of Internal Medicine, 1914 So little is known concerning blood-platelets, and so little interest has been taken in them, that their description by Adami and Nichols 1 is almost fully quoted. If only because they play so important a part in the process of thrombosis it is necessary to have a clear understanding regarding the blood-platelets, or, more accurately, regarding what ...
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Acta Biomedica Scientifica, 2023 Background. In our previously published studies, we demonstrated a high hemostatic activity of a low dose of exogenous fibrin monomer during its systemic administration in a model of dosed liver injury with preliminary inhibition of platelet aggregation.
V. M. Vdovin +6 more
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Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass [PDF]
, 1999 Objectives: The investigation centers on whether there is a reperfusion-induced specific cardiac inflammatory reaction after bypass surgery. Background: Cardiopulmonary bypass (CPB) leads to systemic inflammation.
Becker, Bernhard F. +5 more
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THE BLOOD PLATELETS IN HEMOPHILIA [PDF]
Archives of Internal Medicine, 1916 Hemophilia on account of its striking nature was early recognized as a clinical entity, and has been the subject of many observations. Many theories as to its causation have been advanced. With the development of methods for the study of the blood it has been possible to discard most of the theories concerning this interesting disease.
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