Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E. +4 more
core +1 more source
All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD [PDF]
Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic appears to be waning, there is much concern that vCJD infection may be perpetuated in humans by the ...
Smith, Antony +58 more
core +1 more source
Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death [PDF]
Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages.
Jones, David B. +9 more
core +1 more source
Comparative effect of haemodynamic variables and rheological properties of the blood on the margination and adhesion of leukocytes and platelets [PDF]
The work in this thesis used an in vitro flow system, which incorporated a capillary viscometer, to systematically determine the effects that haemodynamic variables, or rheological properties of the perfused, fluorescently-labelled blood, had on the ...
Watts, Tim
core +7 more sources
Citrate is the recommended anticoagulant for studies on plasma extracellular vesicles (EVs). Because citrate incompletely blocks platelet activation and the release of platelet-derived EVs, we compared EDTA and citrate in that regard.
Naomi C. Buntsma +5 more
doaj +1 more source
BLOOD-PLATELETS AND TUBERCULOSIS [PDF]
So little is known concerning blood-platelets, and so little interest has been taken in them, that their description by Adami and Nichols 1 is almost fully quoted. If only because they play so important a part in the process of thrombosis it is necessary to have a clear understanding regarding the blood-platelets, or, more accurately, regarding what ...
openaire +2 more sources
Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]
Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Welsch, Ulrich +3 more
core +1 more source
THE HISTOGENESIS OF BLOOD PLATELETS [PDF]
1. Under normal circumstances blood platelets are largely derived from the megakaryocyte of the blood-forming organs. 2. The transitional leucocyte, representing a persistent form of the embryonic premegakaryocyte, is a circulating homologue of the megakaryocyte and probably plays some part in normal platelet formation. 3.
openaire +2 more sources
The purpose of the study was to define a role of thrombocytic-vascular hemostasis in the development of pulmonary complications in severe brain injury. Forty-six patients with severe brain injury were studied over time.
Yu. A. Churlyaev, L. Yu. Redkokasha
doaj +1 more source
Dose-dependent effect of canine lyophilized platelet on an in vitro hemodilution model
The transfusion of stored platelets has emerged as an efficient method for treating dogs with thrombocytopenia. However, the availability of fresh platelets is limited in veterinary medicine due to demanding storage conditions. Lyophilized platelets have
Mu-Young Kim, Hyun-Jung Han
doaj +1 more source

