Results 11 to 20 of about 484,220 (201)

Effects of the interactions between platelets with other cells in tumor growth and progression

Frontiers in Immunology, 2023
It has been confirmed that platelets play a key role in tumorigenesis. Tumor-activated platelets can recruit blood cells and immune cells to migrate, establish an inflammatory tumor microenvironment at the sites of primary and metastatic tumors.
Yaxin Li, Haiyan Wang, Zhen Zhao, Yuanming Yang, Zifan Meng, Lifeng Qin   +5 more
doaj   +1 more source

Platelets, Constant and Cooperative Companions of Sessile and Disseminating Tumor Cells, Crucially Contribute to the Tumor Microenvironment

Frontiers in Cell and Developmental Biology, 2021
Although platelets and the coagulation factors are components of the blood system, they become part of and contribute to the tumor microenvironment (TME) not only within a solid tumor mass, but also within a hematogenous micrometastasis on its way ...
Wolfgang M. J. Obermann, Katrin Brockhaus, Johannes A. Eble   +2 more
doaj   +1 more source

Pro-Thrombotic Activity of Blood Platelets in Multiple Sclerosis [PDF]

Cells, 2019
Joanna Saluk-Bijak, Angela Dziedzic, Michal Bijak   +2 more
exaly   +2 more sources

Presence and activity of Fibrinogen like protein 2 in platelets.

PLoS ONE, 2023
BackgroundFibrinogen-like protein 2 (FGL2) is a serine protease capable of converting prothrombin into thrombin (i.e., prothrombinase-like activity) while bypassing the classic coagulation cascade.
Izhack Cherny, Pinhas Hasin, Lital Kalich Philosoph, Yael Shahal-Zimra, Ronit Gurion, Esther Rabizadeh   +5 more
doaj   +1 more source

Design of the Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass SurgeryCentral MessagePerspective

JTCVS Open, 2023
Objective: Dimethylsulfoxide-cryopreserved platelets are being evaluated for treatment of acute hemorrhage in patients with thrombocytopenia or platelet dysfunction when liquid stored platelets are unavailable.
Glenn Whitman, MD, Robert Kramer, MD, Kenichi Tanaka, MD, John Holcomb, MD, G. Michael Fitzpatrick, PhD, Jacob Raphael, MD, Paul Ness, MD   +6 more
doaj   +1 more source

Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]

, 2016
Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Van Aelst, Britt, Vandekerckhove, Philippe   +4 more
core   +2 more sources

Perbedaan Hitung Jumlah Trombosit Menggunakan Darah Vena dan Darah Kapiler

Journal of Health (JOH), 2016
Background: Platelets play a role in hemostasis which is the body's mechanisms to prevent and stop the bleeding. Platelets participate in the effort to close the wound, so that the body does not experience a loss of blood and protected from foreign cells.
Hieronymus Rayi Prasetya, Maria Irena Dentri, Sistiyono Sistiyono   +2 more
doaj   +1 more source

Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]

, 2002
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E., Goetz, Alwin Eduard, Massberg, S., Ney, L.   +3 more
core   +1 more source

Assessment of neonatal, cord, and adult platelet granule trafficking and secretion

Platelets, 2020
Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis.
Anh T. P. Ngo, Jawaad Sheriff, Anne D. Rocheleau, Matthew Bucher, Kendra R. Jones, Anna-Liisa I. Sepp, Lisa E. Malone, Amanda Zigomalas, Alina Maloyan, Wadie F. Bahou, Danny Bluestein, Owen J. T. McCarty, Kristina M. Haley   +12 more
doaj   +1 more source

Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]

, 2017
Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S, Kim, Oleg V, Litvinov, Rustem I, Weisel, John W   +3 more
core   +2 more sources