Contribution of blood platelets to vascular pathology in Alzheimer’s disease
Journal of Blood Medicine, 2013 Cerebral amyloid angiopathy (CAA) is a critical factor in the pathogenesis of Alzheimer’s disease (AD). In the clinical setting, nearly 98% AD patients have CAA, and 75% of these patients are rated as severe CAA.
Wei Zhang, Wei Huang, Fang Jing
semanticscholar +1 more source
Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen +11 more
wiley +1 more source
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]
, 2016 Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine +11 more
core +1 more source
THE VISCOUS METAMORPHOSIS OF THE BLOOD PLATELETS
Journal of Experimental Medicine, 1917 From the experiments above described it is evident that the viscous metamorphosis of the blood platelets in shed blood is intimately associated with the early stages of coagulation and that the presence of calcium is a very important element, though ...
J. Homer Wright, G. Minot
semanticscholar +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Correlation of bioactive components of platelet rich plasma derived from human female adult peripheral blood and umbilical cord blood with age [PDF]
, 2023 Ju Tian +11 more
openalex +1 more source
Arthritis Care &Research, EarlyView.Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech +4 more
wiley +1 more source
Protocol for Murine/Mouse Platelets Isolation and Their Reintroduction in vivo
Bio-Protocol, 2017 Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted methods used in coagulation research for the ...
Jae Im, Ruth Muschel
doaj +1 more source
Optimized gating and reference ranges of reticulated platelets in dogs for the Sysmex XT-2000iV [PDF]
, 2016 Background: Canine reticulated platelets (r-PLTs) i.e., juvenile PLTs reflecting thrombopoiesis can be measured automatically with the hematology analyzer Sysmex XT-2000iV using manual gating options.
Bauer, Natali +5 more
core +2 more sources
ABO Groups in Blood Platelets [PDF]
Nature, 1954 IT has been found that suspensions of blood platelets in normal saline are agglutinated by A- B- and O-sera, just as these sera agglutinate red blood cells of the corresponding blood group. It is thus possible to establish four blood groups for the blood platelets, similar to the blood groups in erythrocytes.
J, GUREVITCH, D, NELKEN
openaire +4 more sources