Results 71 to 80 of about 410,702 (329)
Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]
We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina+9 more
core +1 more source
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
This article answers the question: Our hospital blood bank has started using platelet additive solution (PAS) platelets and psoralen treated platelets.
Coberly, Emily
core +1 more source
BLOOD CELLS PROFILE IN UMBILICAL CORD OF LATE PRETERM AND TERM NEWBORNS
Objective: To describe the hematological profile in cord blood of late preterm and term newborns and compare blood indices according to sex, weight for gestational age and type of delivery.
Anna Carolina Boni Rolim+7 more
doaj +1 more source
Protocol for Murine/Mouse Platelets Isolation and Their Reintroduction in vivo
Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted methods used in coagulation research for the ...
Jae Im, Ruth Muschel
doaj +1 more source
Platelets play a role in transfusion reaction via reactive oxygen species (ROS) generation and CD40 ligand (CD40L) expression. In this study, we aimed to test the hypothesis that the mixing of packed red blood cells (pRBCs) and washed platelets has a ...
Mei-Hua Hu+3 more
doaj +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
The cost of blood in paediatric oncology patients [PDF]
Introduction: Consumption of blood products is significant aiming to treat low cell counts and improve quality of life however 9% to 44% of the total consumption in centres abroad are unjustified.
Baldacchino, Ian+5 more
core
PLATELETS AND BLOOD COAGULATION [PDF]
1. Under dark‐field illumination the platelets of previously cooled mammalian plasma have been observed. During the first two or three minutes they undergo progressive expansion, while clear blebs or spherules begin to appear round their margin. Then the platelets suddenly disintegrate, and the spherules travel swiftly outwards into the surrounding ...
Hugh E. Burke, John Tait
openaire +2 more sources
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source