Results 81 to 90 of about 4,705,585 (363)
Contribution of blood platelets to vascular pathology in Alzheimer’s disease
Journal of Blood Medicine, 2013 Cerebral amyloid angiopathy (CAA) is a critical factor in the pathogenesis of Alzheimer’s disease (AD). In the clinical setting, nearly 98% AD patients have CAA, and 75% of these patients are rated as severe CAA.
Wei Zhang, Wei Huang, Fang Jing
semanticscholar +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Blood platelet kinetics and platelet transfusion [PDF]
Journal of Clinical Investigation, 2013 The discovery of citrate anticoagulant in the 1920s and the development of plastic packs for blood collection in the 1960s laid the groundwork for platelet transfusion therapy on a scale not previously possible. A major limitation, however, was the finding that platelet concentrates prepared from blood anticoagulated with citrate were unsuitable for ...
openaire +3 more sources
Translocating the blood-brain barrier using electrostatics [PDF]
, 2012 Copyright © 2012 Ribeiro,Domingues, Freire,Santos and Castanho. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the ...
Castanho, Miguel A. R. B. +4 more
core +2 more sources
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]
, 2019 We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina +9 more
core +1 more source
, 1912 The hemorrhagic diathesis of chloroform and phosphorus poisoning is without doubt due to a deficiency of fibrinogen in the blood and that of a type of melena neonatorum to a retarded rate or complete failure of blood coagulation.
W. W. Duke
semanticscholar +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
BLOOD CELLS PROFILE IN UMBILICAL CORD OF LATE PRETERM AND TERM NEWBORNS
Revista Paulista de PediatriaObjective: To describe the hematological profile in cord blood of late preterm and term newborns and compare blood indices according to sex, weight for gestational age and type of delivery.
Anna Carolina Boni Rolim +7 more
doaj +1 more source
PLATELETS AND BLOOD COAGULATION [PDF]
Quarterly Journal of Experimental Physiology, 1926 1. Under dark‐field illumination the platelets of previously cooled mammalian plasma have been observed. During the first two or three minutes they undergo progressive expansion, while clear blebs or spherules begin to appear round their margin. Then the platelets suddenly disintegrate, and the spherules travel swiftly outwards into the surrounding ...
Hugh E. Burke, John Tait
openaire +2 more sources