, 2018 Ischemia leading to heart attacks and strokes is the major cause of deaths in the world. Whether an occlusion occurs or not, depends on the ability of a growing thrombus to resist forces exerted on its structure.
Chandran, Vishnu Deep +3 more
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A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. [PDF]
, 1985 We have previously characterized a monoclonal antibody, S12, that binds only to activated platelets (McEver, R.P., and M.N. Martin, 1984, J. Biol. Chem., 259:9799-9804). It identifies a platelet membrane protein of Mr 140,000, which we have designated as
Bainton, DF +4 more
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Spatial confinement alters morphology, spreading dynamics, and mechanics of adherent platelets
Biophysical ReportsPlatelets are small blood cells involved in hemostasis and wound healing. After activation, platelets interact with their surrounding environment and respond to biochemical and mechanical stimuli by mechanosensitive and haptotactic mechanisms.
Johanna G. Rodríguez +4 more
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Isolation of Human Platelets (Thrombocytes)
The Scientific World Journal, 2002 Platelets from human blood can be isolated in high yield by centrifugation of whole blood over an iodixanol density barrier of 1.063 g/ml. The separation from all of the blood cells (which form a pellet) is based on the slower sedimentation velocity of ...
John Graham
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Modulation of interferon-[alpha] secretion by activated platelets in systemic lupus erythematosus. [PDF]
, 2008 Type I interferons play a key role in systemic lupus erythematosus (SLE) pathogenesis as an "IFN signature" is found in the majority of patients with active SLE.
Bernard Weill +8 more
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Force generation in human blood platelets by filamentous actomyosin structures. [PDF]
Biophys J, 2023 Zelená A +6 more
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Adhesion and Activation of Blood Platelets on Laser-Structured Surfaces of Biomedical Metal Alloys. [PDF]
J Funct Biomater, 2023 Kamińska M +5 more
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The cost of blood in paediatric oncology patients [PDF]
, 2016 Introduction: Consumption of blood products is significant aiming to treat low cell counts and improve quality of life however 9% to 44% of the total consumption in centres abroad are unjustified.
Baldacchino, Ian +5 more
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How different are blood platelets from women or men, and young or elderly people? [PDF]
Haematologica, 2023 De Gaetano G, Bonaccio M, Cerletti C.
europepmc +1 more source
Increased vesiculability of platelets in 24 patients with gastrointestinal cancer
Zdravniški Vestnik, 2014 Background: Cell nanovesicles (NVs) are small (mostly nano-sized) membrane-enclosed cell fragments that are pinched off from the cell due to rearrangement of its constituents.
Eva Ogorevc +4 more
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