Results 101 to 110 of about 1,051,412 (371)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Blood Protein Variations in Asian Macaques

, 1972
For the purpose of investigating the extent of genetic variability in macaque monkeys, we have examined various blood proteins, known to be polymorphic or to show inherited variations in man, in thousand samples comprising several species of macaques. We
G. Ishimoto
semanticscholar   +1 more source

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source

GENETIC VARIATION IN THREE BREEDS OF INDONESIAN LOCAL DUCKS BASED ON BLOOD AND EGG WHITE PROTEIN POLYMORPHISM

Journal of the Indonesian Tropical Animal Agriculture, 2014
A study of genetic variation of four blood protein loci and three egg white loci in three breeds ofIndonesian local ducks (Magelang duck = MAD, Tegal duck = TED and Mojosari duck= MOD) wasinvestigated by using polyacrilamide gel electrophoresis (PAGE ...
S. Johari, S. Ekasari, E. Kurnianto
doaj   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Blood Protein Residues on Lithic Artifacts from Two Archaeological Sites in the De Long Mountains, Northwestern Alaska

, 1996
Immunological analysis of blood residues was performed on 25 lithic artifacts from two archaeological sites (DEL-166 and DEL-168) in the De Long Mountains of northwestern Alaska. Blood residues occur on five artifact types: retouched flakes; end scrapers;
S. C. Gerlach, M. Newman, E. Knell, E. Hall   +3 more
semanticscholar   +1 more source

Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]

, 2007
The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria, Boulangé, Alain, Brizard, Jean-Paul, Courtois, Pierrette, Cuny, Gérard, Daulouède, Sylvie, Frutos, Roger, Grébaut, Pascal, Holzmuller, Philippe, Peltier, Jean-Benoît, Vincendeau, Philippe   +10 more
core  

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source

A retrospective study of the relative utility of electrophoresis in the investigation of serum proteins

Universa Medicina
Background Serum protein electrophoresis (SPE) is widely used for diagnosis, management and monitoring of different immune disorders. Serum protein alterations provide valuable insights about these disorders.
Gusdanis Alberto Campos García, Yulien Fernández Romay , Naga Raju Maddela, Aron Zamora Cedeño , Diego Talledo Pinargote , Ivón Howland Álvarez   +5 more
doaj   +1 more source

Green tea extract supplementation ameliorates CCl4-induced hepatic oxidative stress, fibrosis, and acute-phase protein expression in rat

Journal of the Formosan Medical Association, 2012
We evaluated the long-term effects of green tea extract (GTE) supplementation on oxidative stress, biliary acute phase protein expression, and liver function in CCl4-induced chronic liver injury.
Guo-Dung Hung, Ping-Chia Li, Hsuan-Shu Lee, Huei-Min Chang, Chiang-Ting Chien, Kuang-Lun Lee   +5 more
doaj   +1 more source