Quo vadis blood protein adductomics? [PDF]
Archives of Toxicology, 2021 AbstractChemicals are measured regularly in air, food, the environment, and the workplace. Biomonitoring of chemicals in biological fluids is a tool to determine the individual exposure. Blood protein adducts of xenobiotics are a marker of both exposure and the biologically effective dose.
Gabriele Sabbioni, Billy W. Day
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Tin speciation in the blood plasma of workers occupationally exposed in a cassiterite ore processing industry [PDF]
Saúde em Debate, 2022 Mining is a high-risk activity due to its dangerous processes. Tin (Sn) is obtained from cassiterite ore and mining activities expose workers to the metal. Chronic exposure to Sn may cause pneumoconiosis, gastrointestinal and hematological effects, among
Débora Resende de Souza Lima +4 more
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The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins. [PDF]
BMC Med Genomics, 2019 Background The conditions of space flight have a significant effect on the physiological processes in the human body, yet the molecular mechanisms driving physiological changes remain unknown.
Kashirina DN +8 more
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Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]
, 2012 The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey +54 more
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The protein organization of a red blood cell [PDF]
Cell Reports, 2021 SUMMARYRed blood cells (RBCs, erythrocytes) are the simplest primary human cells, lacking nuclei and major organelles, and instead employing about a thousand proteins to dynamically control cellular function and morphology in response to physiological cues.
Wisath Sae-Lee +12 more
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Haematologica, 2016 It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derived ...
Nicoletta Sorvillo +8 more
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Structural insight into mitochondrial β-barrel outer membrane protein biogenesis
Nature Communications, 2020 The Sorting and Assembly Machinery (SAM) complex folds beta-barrel proteins and inserts them into the mitochondrial outer membrane. Here authors report cryoEM structures of the SAM complex from Myceliophthora thermophila, which reveals a GST-like fold ...
Kathryn A. Diederichs +8 more
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Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease [PDF]
, 2014 Buruli ulcer is a skin disease caused by Mycobacterium ulcerans that is spreading in tropical countries, with major public health and economic implications in West Africa.
AA Pahlevan +48 more
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Protein absorption by blood corpuscles [PDF]
Experimental Biology and Medicine, 1916 If 1 per cent. goat serum is added to freshly drawn defibrinated normal rabbit blood, the mixture incubated for one hour, and then separated by centrifugation into serum and corpuscle fractions, a titration of the serum fraction by specific precipitin methods will usually show but 25 per cent.
Manwaring, W. H., Kusama, Y.
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A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation
Haematologica, 2018 HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills.
Maaike Rijkers +11 more
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