Results 31 to 40 of about 10,648,386 (353)

Effect of Pre-Incubation of Electrospun Silk Fibroin Scaffold in Complete and Serum-Free Media on Survival and Proliferation of Rat Bone Marrow Mesenchymal Stem Cells

Medical Laboratory Journal, 2022
Background and objectives: Developing scaffolds is important for tissue engineering and repairing damaged tissues. The present study aimed to investigate effects of pre-incubation of an electrospun silk fibroin scaffold in complete and serum-free media ...
Maryam Janitermi, esmail fattahi, seyed Gholam ali Jorsaraei   +2 more
doaj  

Efficacy of mineral and organic adsorbent in alleviating harmful effects of zearalenone on pig blood serum protein status [PDF]

Veterinarski Glasnik, 2008
The influence of zearalenone on blood serum protein status and the feasibility of utilizing a modified clinoptilolite and esterified glucomannan to alleviate its harmful effects was examined in two trials, 31 and 29 days long, conducted on a total of 64 ...
Nešić Ksenija, Stevanović Jelka, Sinovec Zlatan   +2 more
doaj   +1 more source

Defining blood-induced microglia functions in neurodegeneration through multiomic profiling

Nature Immunology, 2023
Blood protein extravasation through a disrupted blood–brain barrier and innate immune activation are hallmarks of neurological diseases and emerging therapeutic targets.
Andrew S. Mendiola, Zhaoqi Yan, Karuna Dixit, Jeffrey R. Johnson, Mehdi Bouhaddou, A. Meyer‐Franke, Min-Gyoung Shin, Yu Yong, Ayushi Agrawal, Eilidh Macdonald, Gayathri Muthukumar, Clairice Pearce, Nikhita Arun, Belinda S. Cabriga, R. Meza-Acevedo, M. D. P. Alzamora, S. Zamvil, Alexander R. Pico, J. Ryu, N. Krogan, K. Akassoglou   +20 more
semanticscholar   +1 more source

Creation of a federated database of blood proteins: a powerful new tool for finding and characterizing biomarkers in serum

Clinical Proteomics, 2014
Protein biomarkers offer major benefits for diagnosis and monitoring of disease processes. Recent advances in protein mass spectrometry make it feasible to use this very sensitive technology to detect and quantify proteins in blood.
John G. Marshall, Peter Bowden, J. Schmit, F. Betsou   +3 more
semanticscholar   +1 more source

Hepatitis B Virus Protein X Induces Degradation of Talin-1

Viruses, 2016
In the infected human hepatocyte, expression of the hepatitis B virus (HBV) accessory protein X (HBx) is essential to maintain viral replication in vivo.
Maarten A. A. van de Klundert, Maartje van den Biggelaar, Neeltje A. Kootstra, Hans L. Zaaijer   +3 more
doaj   +1 more source

The Bor1 elevator transport cycle is subject to autoinhibition and activation

Nature Communications
Boron, essential for plant growth, necessitates precise regulation due to its potential toxicity. This regulation is achieved by borate transporters (BORs), which are homologous to the SLC4 family.
Yan Jiang, Jiansen Jiang
doaj   +1 more source

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages

Blood Advances, 2017
: Internalization of ADAMTS13 by macrophages may contribute to its clearance from the circulation. Here we investigated endocytic mechanisms that contribute to the uptake of ADAMTS13 by macrophages. Human monocyte-derived macrophages were used to monitor
Fabian C. Verbij, Nicoletta Sorvillo, Paul H.P. Kaijen, Johana Hrdinova, Ivan Peyron, Rob Fijnheer, Anja ten Brinke, Alexander B. Meijer, Floris P.J. van Alphen, Timo K. van den Berg, Jonas J.H. Graversen, Soren K. Moestrup, Jan Voorberg   +12 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source