Results 121 to 130 of about 87,615,486 (243)

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source

Table_1_Blood urea nitrogen to serum albumin ratio is associated with all-cause mortality in patients with AKI: a cohort study.docx

BackgroundThis study aims to investigate the relationship between blood urea nitrogen to serum albumin ratio (BAR) and all-cause mortality in patients with acute kidney injury (AKI) and evaluate the effect of BAR on the prognosis of AKI.MethodsAdult ...
Yifan Zhang (119570), Yue Shi (128342), Yu Zhang (12946), Hangyu Duan (17993554), Xiujie Shi (17993557), Qi Zhang (28502), Jing Liu (38537), Mingming Zhao (760369)   +7 more
core   +1 more source

The pathophysiology of fluid removal during haemodialysis: implications for blood volume monitoring and determination of dry weight. [PDF]

, 2007
The aim of the research was to characterise the pathophysiology of ultrafiltration (UF) during haemodialysis (HD) using a range of assessment tools. The hypothesis was that objective monitoring would facilitate accurate estimation of dry weight (DW) and ...
Mitra, S., Mitra, Sandip
core  

Prediction of Long‐Term Prognosis in Patients With Hepatocellular Carcinoma Using the National Clinical Database Risk Calculator

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi, Kenichiro Araki, Norio Kubo, Takamichi Igarashi, Shunsuke Kawai, Kei Hagiwara, Kouki Hoshino, Ryo Muranushi, Ken Shirabe   +8 more
wiley   +1 more source

Table_2_Blood urea nitrogen to serum albumin ratio is associated with all-cause mortality in patients with AKI: a cohort study.docx

BackgroundThis study aims to investigate the relationship between blood urea nitrogen to serum albumin ratio (BAR) and all-cause mortality in patients with acute kidney injury (AKI) and evaluate the effect of BAR on the prognosis of AKI.MethodsAdult ...
Yifan Zhang (119570), Yue Shi (128342), Yu Zhang (12946), Hangyu Duan (17993554), Xiujie Shi (17993557), Qi Zhang (28502), Jing Liu (38537), Mingming Zhao (760369)   +7 more
core   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Cross-sectional study investigating the relationship between pit recovery time and serum albumin levels in bilateral lower extremity pitting oedema

BMJ Open
Objectives In this study, we re-evaluated the relationship between pit recovery time (PRT) and serum albumin levels and elucidated the factors influencing PRT.Design Cross-sectional study.Setting Patients who visited the outpatient department or were ...
Ryosuke Ono, Ken Horibata
doaj   +1 more source

Autoreactivity Versus Autoimmunity: Characteristics of Autoantigen‐Specific CD4 T Cells in Rheumatoid Arthritis and Health

Arthritis &Rheumatology, EarlyView.
Objective CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis. Characterizing these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next ...
James A. Stanway, Daniel Peters, Helen Waller, Jeremy Lakey, Henrique De Paula Lemos, Kristian Williams, Abbie Degnan, Julie Diboll, Abdul Mannan Baru, David Tough, Arthur G. Pratt, Catharien M.U. Hilkens, Amy E. Anderson, John D. Isaacs   +13 more
wiley   +1 more source

Longitudinal Changes of BMI and Renal Function Biomarkers During the Final 3 Years of Life Among Hospitalized Patients with Schizophrenia in Japan: A Preliminary Study

Psychiatry International
Patients with schizophrenia face high mortality from physical comorbidities; nonetheless, the gradual physiological decline preceding death is not well characterized.
Yoshihiro Mifune, Hirokazu Ito, Krishan Soriano, Leah Anne Bollos, Toshiya Akiyama, Kyoko Osaka, Hidehiro Umehara, Itsuro Endo, Rick Yiu Cho Kwan, Anson Chui Yan Tang, Kazushi Mifune, Tetsuya Tanioka   +11 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source