Results 91 to 100 of about 1,516,611 (334)
RNA Isolation and Northern Blot Analysis
Bio-Protocol, 2014 The northern blot is a technique used in molecular biology research to study gene expression by detection of RNA in a sample. With northern blotting it is possible to observe particular gene expression levels during differentiation, morphogenesis, as ...
Ying Liao +5 more
doaj +1 more source
La relation agriculteurs/société à travers la mise en oeuvre des politiques des gestion de l'eau dans le sud-ouest européen [PDF]
, 2002 International audienceLes politiques de l'eau française et espagnole ont tendu, dès le XIX ème siècle, vers une gestion sectorielle de la ressource visant à maximiser l'exploitation des « gisements » en eau au moyen d'aménagements lourds.
Blot, Frédérique
core +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Blots of ink in experimental psychology. [PDF]
, 1897 George Van Ness Dearborn
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Responses of Homeless Men to Baron M-Limits Blots [PDF]
, 1956 Boris M. Levinson, Sam Baron
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Les cercles de Pierre ou "Cromlechs" en Pays Basque de France. [PDF]
, 1982 Los círculos de piedra abundan en las montañas vascas, hay tres tipos: cromlechs, túmulos-cromlechs y túmulos simples que son variantes de una misma idea funeraria, que es el rito de la incineración que se practicaba al final de la Edad de Bronce y ...
Blot, Jacques
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
The substitution of asbestos cloth for blotting paper in Mr. Adams' modification of Mr. Abraham's process of milk analysis [PDF]
, 1887 W. Michael Johnstone
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source