Results 61 to 70 of about 1,516,611 (334)

Les cromlechs d'Apatesaro I et I bis (Compte rendu de fouilles). [PDF]

Munibe Antropologia-Arkeologia, 1984
Se da cuenta de los resultados obtenidos en la excavación de los cromlechs de Apatesaro, datados en el primer milenio a.C.
Jacques Blot
doaj  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

On the Almost Everywhere Continuity

, 2014
The aim of this paper is to provide characterizations of the Lebesgue-almost everywhere continuity of a function f : [a, b] $\rightarrow$ R. These characterizations permit to obtain necessary and sufficient conditions for the Riemann integrability of f
Blot, Joël
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

On the multiplier rules

, 2014
We establish new results of first-order necessary conditions of optimality for finite-dimensional problems with inequality constraints and for problems with equality and inequality constraints, in the form of John's theorem and in the form of Karush-Kuhn-
Blot, Joël
core   +1 more source

Du chaos financier au K.O. économique [PDF]

, 1994
Depuis le mois d’août 2007, l’économie mondiale est frappée par une crise financière majeure qui plonge de nombreux pays dans les affres de la récession.
Blot, Christophe, Timbeau, Xavier
core   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

DNA Slot Blot Repair Assay

Bio-Protocol, 2015
Ultraviolet (UV) irradiation induces helix distorting photolesions such as cyclobutane pyrimidine dimers (CPD) and pyrimidine-pyrimidone (6-4) photoproducts (6-4PP) which threaten genomic integrity if unrepaired.
Jeong-Min Park, Tae-Hong Kang
doaj   +1 more source

Discrete time pontryagin principles in banach spaces

, 2017
The aim of this paper is to establish Pontryagin's principles in a dicrete-time infinite-horizon setting when the state variables and the control variables belong to infinite dimensional Banach spaces. In comparison with previous results on this question,
Bachir, Mohammed, Blot, Joël
core  

Gestion de l'eau et modèle de développement en débat en Espagne [PDF]

, 2006
Les habitants du bassin du Segura, situé au Sud de l'Espagne, ont bien du mal à comprendre le Décret Royal du 18 juin 2004 qui, pour eux, constitue un retournement sans précédent, au regard de la politique de gestion de l'eau menée en Espagne depuis plus
Blot, Frédérique
core   +1 more source