Results 91 to 100 of about 93,995 (262)

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

FXTAS and the Spectrum of FMR1 Premutation‐Associated Phenotypes in Latin America: A Scoping Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Fragile X–associated tremor/ataxia syndrome (FXTAS) is a late‐onset neurodegenerative disorder caused by FMR1 premutation expansions (55–200 CGG repeats). Although well described in populations of predominantly European ancestry, FXTAS remains poorly characterized in Latin America due to limited awareness, restricted access to ...
Amy Schmidmajer   +6 more
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

open access: yesPrecision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run   +7 more
wiley   +1 more source

Non‐triazine photosystem II inhibitors provide effective control of metabolic atrazine‐resistant Amaranthus tuberculatus

open access: yesPest Management Science, EarlyView.
Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez   +5 more
wiley   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

open access: yesSmall, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo   +7 more
wiley   +1 more source

‘Pro‐Germans in the Pulpits’: The Queensland Presbyterian Church and the Great War

open access: yesJournal of Religious History, EarlyView.
During World War I, Protestant churches in Australia, on the whole, enthusiastically supported the war effort. The Queensland Presbyterian Church was a significant exception. This study analyses discord and tensions among its clergymen about what constituted an appropriate response to the war.
Mark Cryle
wiley   +1 more source

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

open access: yesIntegrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu   +6 more
wiley   +1 more source

Northern Blot

open access: yesProtocol Exchange, 2015
Shicheng Su, Shicheng Su, Di Huang
openaire   +1 more source

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