Results 161 to 170 of about 98,102 (238)

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Using circular RNAs to target toxic RNA-binding proteins in amyotrophic lateral sclerosis. [PDF]

Mol Ther Methods Clin Dev
Hollensen AK, Sørensen MH, Thomsen SV, Thomsen HS, Damgaard CK.   +4 more
europepmc   +1 more source

Local News Deserts and Community Social Capital Erosion

Journal of Regional Science, EarlyView.
ABSTRACT The disappearance of local newspapers across the United States has sparked growing concern about its implications for community life in rural America. This study examines the societal consequences of local news deserts, focusing on three critical dimensions of community social capital: crime, civic engagement, and political polarization. Using
Tess Haddock, K. Aleks Schaefer, Brian E. Whitacre, Trey Malone   +3 more
wiley   +1 more source

5'-terminal glycosylation of protein-coding transcripts: An epitranscriptomic modification that prolongs mRNA lifetimes. [PDF]

Proc Natl Acad Sci U S A
Banerjee T, Luciano DJ, Belasco JG.
europepmc   +1 more source

Potential vectors of Leishmaniases in the Environmental Protection Area and Tinguá Federal Biological Reserve, Municipality of Nova Iguaçu, Rio de Janeiro, Brazil

Medical and Veterinary Entomology, EarlyView.
This study was to describe the composition of sand fly fauna, detect potential vectors of Leishmania spp. in the Tinguá district, an ATL endemic, Rio de Janeiro, Brazil. Seven species of vectorial importance in the epidemiological cycle of leishmaniasis was observed: Nyssomyia intermedia, Migonemyia migonei, Pintomyia fischeri, Psychodopygus hirsutus ...
Antônio L. F. Santana, Alfredo C. R. Azevedo, Margarete M. S. Afonso, Bruno M. Carvalho, Vanessa R. Vieira, Simone M. Costa, Júlia S. Silva, Thais A. Pereira, Daniela P. Pereira, Maurício L. Vilela   +9 more
wiley   +1 more source

Yeast pre-rRNA is processed at the A' site. [PDF]

MicroPubl Biol
Dutca LM, Freed EF, Baserga SJ.
europepmc   +1 more source

The maize mitogen‐activated protein kinase kinase kinase gene ZmMAPKKK45 is associated with multiple disease resistance

New Phytologist, EarlyView.
Summary Southern leaf blight (SLB), caused by the necrotrophic fungus Cochliobolus heterostrophus, is a major foliar disease of maize (Zea mays) world‐wide. A genome‐wide association study was performed to dissect the genetic basis of SLB resistance in maize. Functional validation was performed using mutant and transgenic analyses.
Tao Zhong, Bode Olukolu, Yang Bian, Shang Xue, Randall J. Wisser, Peter S. Ojiambo, James B. Holland, Qin Yang, Peter Balint‐Kurti   +8 more
wiley   +1 more source

Mammalian tRNA acetylation determines translation efficiency and tRNA quality control. [PDF]

Nat Commun
Liu N, Liu B, Ma CR, Cai Z, Wang JT, Chai ZQ, Zhu N, Shao T, Chen YL, Lin Y, Wang Y, Xu H, Zhou XL.   +12 more
europepmc   +1 more source

Symbiosis‐associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula

New Phytologist, EarlyView.
Summary To address a critical gap in understanding amino acid transport in legume–Rhizobium symbiosis, we investigated the role of symbiosis‐associated USUALLY MULTIPLE ACIDS MOVE IN AND OUT TRANSPORTERS (UMAMITs) in Medicago truncatula nodulation.
Courtney S. Winning, María Isabel Rubia, Wei Liu, Daniel Bronitt, Ángel María Zamarreño, José María García‐Mina, Penelope Smith, Estíbaliz Larrainzar, Michael A. Djordjevic   +8 more
wiley   +1 more source

Precision hyperthermia-induced HSP20 inhibits gastric cancer cell invasion, migration, and proliferation. [PDF]

Discov Oncol
Sun Q, Long Z, Wang Y, Ren J, Wang D.
europepmc   +1 more source