Results 151 to 160 of about 93,995 (262)

Protocol for monitoring mRNA translation and degradation in human cell-free lysates. [PDF]

STAR Protoc
Schwaller N, Karousis ED.
europepmc   +1 more source

From Everyman to Hamlet: A Distant Reading

Renaissance Studies, EarlyView.
Abstract The sixteenth century sees English drama move from Everyman to Hamlet: from religious to secular subject matter and from personified abstractions to characters bearing proper names. Most modern scholarship has explained this transformation in terms originating in the work of Jacob Burckhardt: concern with religion and a taste for ...
Vladimir Brljak
wiley   +1 more source

Elucidating the molecular mechanisms of Daifu decoction in ulcerative colitis treatment through a multi-omics framework and experimental verification. [PDF]

Front Immunol
Zhao Y, Cui D, Gong Y, Xiao Y.
europepmc   +1 more source

Teaching New Religious Movements Historically: Distance, Empathy, and Cults in the Classroom

Teaching Theology &Religion, EarlyView.
ABSTRACT Resistance to understanding the beliefs of modern New Religious Movements (NRMs) is well‐known to those who teach in the area. This paper builds on Eugene Gallagher's repurposing of “methodological belief” for college classes on NRMs by suggesting that scholars and teachers in the field of religious studies engage methods and content drawn ...
Douglas FitzHenry Jones
wiley   +1 more source

HIV-1-encoded circular RNA enhances viral transcription through Tat binding. [PDF]

Nat Microbiol
Obi P, Yan L, Dujsikova A, Yeh YJ, Li I, Mueller NL, Back H, Yi B, Liu N, Mbadugha F, Yu H, Brown C, St Denis K, Landry ML, Sumigray K, Emu B, Ho YC, Chen YG.   +17 more
europepmc   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

The interferon-inducible MxB large GTPase attenuates hepatitis B virus replication by activating the RIG-I innate immunity signaling pathway. [PDF]

Sci Rep
Onuki M, Inoue J, Doi K, Ninomiya M, Sano A, Tsuruoka M, Sato K, Sawahashi S, Ouchi K, Watanabe K, McNiven MA, Masamune A.   +11 more
europepmc   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

Suppressing CDCA8/CDK1 improves oral squamous cell carcinoma by modulating proliferation, apoptosis, cell cycle and migration. [PDF]

Discov Oncol
Zhu J, Chu C, Xue Y, Guan W, Qiu J, Guo A, Chu W.   +6 more
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source