Results 51 to 60 of about 1,606,720 (296)

The plasma membrane carbonic anhydrase in murine hepatocytes identified as isozyme XIV

BMC Gastroenterology, 2002
Background Biochemical and histochemical studies have both previously indicated plasma membrane-associated carbonic anhydrase (CA) activity in hepatocytes which has been assumed to be CA IV.
Rajaniemi Hannu, Hakkola Jukka, Parkkila Anna-Kaisa, Kaunisto Kari, Kivelä Antti J, Parkkila Seppo, Waheed Abdul, Sly William S   +7 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Northern Blot Analysis [PDF]

, 2019
Abstract The whole workflow for the quantification of specific transcripts by Northern blot analysis is described in detail, including RNA isolation, probe generation via labelling with Dig-dUTP, hybridization, signal visualization and quantification.
Madeleine Huber, Jörg Soppa
openaire   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

A Review of Nanotechnology in microRNA Detection and Drug Delivery

Cells
MicroRNAs (miRNAs) are small, non-coding RNAs that play a crucial role in regulating gene expression. Dysfunction in miRNAs can lead to various diseases, including cancers, neurological disorders, and cardiovascular conditions.
Hsiuying Wang
doaj   +1 more source

Sensitive Nonradioactive Dot Blot/Ribonuclease Protection Assay for Quantitative Determination of mRNA

BioTechniques, 1997
We have developed a simple and sensitive method for the rapid quantitation of mRNA from cell cultures and small tissue samples. The method combines the high sensitivity and specificity of the ribonuclease protection assay with simple handling and rapid ...
Jinghai Zhan, H. Dariush Fahimi, Alfred Vöelkl   +2 more
doaj   +1 more source

Vision for Northern Territory Public Libraries 2017-2023

, 2017
"This document confirms the many ways in which libraries add value to their communities and identifies areas for future development. It will underpin the ways in which the Northern Territory Government will continue to support public library services ...
Northern Territory Library
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Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

A recombination point is conserved in the mitochondrial genome of higher plant species and located downstream from the cox2 pseudogene in Solanum tuberosum L.

Genetics and Molecular Biology, 2006
The potato (Solanum tuberosum L.) mitochondrial cox3/sdh4/pseudo-cox2 gene cluster has previously been identified by heterologous hybridization using a Marchantia polymorpha sdh4 probe.
Susely F.S. Tada, Anete P. Souza
doaj   +1 more source

Northern Territory Patients Assistance Travel Scheme (PATS) : information for staff

, 1986
The Northern Territory Government, through PATS, provides financial assistance to people who live in isolated areas and need specialist medical services.
Northern Territory Department of Health
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