Results 141 to 150 of about 42,313 (282)
Antagonistic Activity of Bacteria Isolated from Apple in Different Fruit Development Stages against Blue Mold Caused by Penicillium expansum. [PDF]
Plant Pathol J, 2021 López-González RC +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Biological changes during ripening of cheese mold [PDF]
, 2010 Má bakalářská práce se věnuje změnám složek mléka při zrání plísňových sýrů. Je v ní uvedena historie plísňových sýrů, rozdělení plísňových sýrů a jejich výrobní postup, charakteristika ušlechtilých plísní uplatňující se při výrově a zrání.
Chocholáč, Martin
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Visibility algorithms for mold and die design. [PDF]
, 1992 Algorithms are developed for selecting optimal parting directions in mold and die design. Based on the condition for demoldability, two levels of visibility--complete and partial visibility--are defined.
Chen, Lin-Lin
core
CONTROL OF BLUE MOLD ON STORAGED APPLES
, 1995 Com o objetivo de controlar o mofo azul, podridão que ataca a maçã em pós-colheita, foram testados os seguintes fungicidas e respectivas dosagens de ingredientes ativos por 100 litros de água: Tiofanato-metflico —0,07; dicloran — 0,125; tiofanato molifico + dicloran — 0,07 + 0,100; triflumizole — 0,03; diniconazole — 0,0025 e thiabendazole — 0,09.
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source