Results 61 to 70 of about 272,370 (331)

TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals. [PDF]

, 2019
The gut microbiota contributes to host health and fitness, and imbalances in its composition are associated with pathology. However, what shapes microbiota composition is not clear, in particular the role of genetic factors.
Berg, Maureen, Cho, Juhyun, Crits-Christoph, Alex, Monnin, David, Nelson, Lydia, Shapira, Michael   +5 more
core   +2 more sources

TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation

Bone Research, 2015
Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases.
M. S. Rahman, Naznin Akhtar, H. M. Jamil, R. Banik, S. M. Asaduzzaman   +4 more
semanticscholar   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans

Cell & Bioscience, 2022
Background Bone morphogenetic protein (BMP) is a phylogenetically conserved signaling pathway required for development that is aberrantly expressed in several age-related diseases including cancer, Alzheimer’s disease, obesity, and cardiovascular disease.
Mehul Vora, Arindam Mondal, Dongxuan Jia, Pranya Gaddipati, Moumen Akel, John Gilleran, Jacques Roberge, Christopher Rongo, John Langenfeld   +8 more
doaj   +1 more source

Regulation of Phosphatase Homologue of Tensin Protein Expression by Bone Morphogenetic Proteins in Prostate Epithelial Cells [PDF]

, 2010
Phosphatase homologue of tensin (PTEN) is the key endogenous inhibitor of phosphoinositide signaling and is the most commonly mutated gene in human prostate cancer.
Dan Theodorescu, Travis Jerde, Wade Bushman, Zhong Wu   +3 more
core   +2 more sources

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

IGF-1 enhances the osteogenic activity of BMP-6 in vitro and in vivo [PDF]

, 2017
Bone morphogenetic protein-2 (BMP-2) is widely used in orthopedic surgery and bone tissue engineering because of its strong osteogenic activity. However, BMP-2 treatments have several drawbacks and alternatives are being explored.
Becerra-Ratia, Jose, Rico-Llanos, Gustavo Adolfo, Visser, Rick   +2 more
core  

Enhancing CoFe Catalysts with V2CTX MXene‐Derived Materials for Anion Exchange Membrane Electrolyzers

Advanced Functional Materials, EarlyView.
MXene dervied CoFe composites show increased initial Oxygen Evolution Reaction (OER) activity compared to the pure CoFe and MXene in an Anion Exchange Membrane device. Vanadium vacancies in the MXene plays a role in increased OER activity and hinders Fe leaching in the AEM device over using the pure V2C MXene as a support material for the CoFe ...
Can Kaplan, Karuppasamy Dharmaraj, Thorsten Schultz, Leiqiang Qin, Ningjun Chen, Danielle A. Douglas‐Henry, Bastian Schmiedecke, Merve Buldu‐Akturk, Axel Zuber, Iris Dorbandt, Maximilian Reinhardt, Yael Rodriguez‐Ayllon, Yan Lu, Valeria Nicolosi, Norbert Koch, Johanna Rosen, Michelle P. Browne   +16 more
wiley   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Pleading Securities Fraud [PDF]

, 2001
Hyaluronan based hydrogel coatings can mimic extracellular matrix components and incorporate growth factors that can be released during a progressive degradation while new tissue regenerates.
Bergman, Berts, Best, Buddula, Chiba, Ciccone, Cubitt, Feiler, Fraser, Golub, Haxaire, Hench, Heymann, Hulsart-Billström, Hunziker, Höök, Kang, Katzer, Liu, Martinez-Sanz, Martínez-Sanz, Morra, Navarro, Nayab, Park, Patterson, Piskounova, Polunina, Sauerbrey, Scheufler, Serro, Vasikaran, Voinova, Voinova, Wozney, Yamanlar, Yang, Yoshinari, Zara, Åberg   +39 more
core   +4 more sources