Results 71 to 80 of about 272,370 (331)

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells. [PDF]

PLoS ONE, 2010
Bone Morphogenetic Protein (BMP) signaling pathways are involved in differentiation of stem cells into diverse cell types, and thus BMPs can be used as main guidance molecules for in vitro differentiation of human stem cells.We have analyzed the ability ...
Elvira Valera, Michael J Isaacs, Yasuhiko Kawakami, Juan Carlos Izpisúa Belmonte, Senyon Choe   +4 more
doaj   +1 more source

BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors

Development, 2016
The pseudostratified epithelium of the lung contains ciliated and secretory luminal cells and basal stem/progenitor cells. To identify signals controlling basal cell behavior we screened factors that alter their self-renewal and differentiation in a ...
Tomomi Tadokoro, Xia Gao, C. Hong, Danielle F Hotten, B. Hogan   +4 more
semanticscholar   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

A Message Passing Algorithm for the Minimum Cost Multicut Problem [PDF]

, 2017
We propose a dual decomposition and linear program relaxation of the NP -hard minimum cost multicut problem. Unlike other polyhedral relaxations of the multicut polytope, it is amenable to efficient optimization by message passing.
Andres, Bjoern, Swoboda, Paul
core   +4 more sources

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

A Comparative Study on New Design Fixation Plate for Parasymphysis of Mandible Fracture with Conventional System

Journal of Pharmacy and Bioallied Sciences
Background: A new non-compression MP has been developed that offers similar benefits to 3D plates and is easier to fix in the PS region (R), as the conceptual design of the plates will allow fx in the PSR while retaining the 3D geometry of the plate. Aim:
Yusuf Ronad, CH V K N S N Moorthy, Pratap Mane, Lishoy W. Rodrigues, Sana Anwar, Dhanu Priya Patel   +5 more
doaj   +1 more source

Regeneration of Bone- and Tendon/Ligament-Like Tissues Induced by Gene Transfer of Bone Morphogenetic Protein-12 in a Rat Bone Defect [PDF]

Journal of Tissue Engineering, 2010
Members of the bone morphogenetic protein (BMP) family have diverse physiological roles. For instance, BMP-2 stimulates osteogenesis, while BMP-12 induces the formation of tendon/ligament-like tissues. Here, we designed a study to
Shinji Kuroda, Nobuhiro Goto, Michiko Suzuki, Kazutaka Kaneda, Keiichi Ohya, Hitoyata Shimokawa, Shohei Kasugai   +6 more
doaj   +1 more source

Salivary inflammatory biomarkers during initial orthodontic tooth movement [PDF]

, 2016
BACKGROUND: Orthodontic tooth movement is a complex process involving a number of inflammatory and anabolic/catabolic pathways. Further, successful treatment depends on proper timing of orthodontic measures with regard to patient’s growth spurt ...
Serrenho, Ana
core   +1 more source

Characterizing the easy-to-find subgraphs from the viewpoint of polynomial-time algorithms, kernels, and Turing kernels [PDF]

, 2015
We study two fundamental problems related to finding subgraphs: (1) given graphs G and H, Subgraph Test asks if H is isomorphic to a subgraph of G, (2) given graphs G, H, and an integer t, PACKING asks if G contains t vertex-disjoint subgraphs isomorphic
Jansen, BMP, Marx, Dániel
core   +1 more source