Results 141 to 150 of about 32,745 (240)

Comparison of Cell Viability and Embryoid Body Size of Two Embryonic Stem Cell Lines After Different Exposure Times to Bone Morphogenetic Protein 4

Iranian Journal of Medical Sciences, 2015
Background: Activation of bone morphogenetic protein 4 (BMP4) signaling pathway in embryonic stem (ES) cells plays an important role in controlling cell proliferation, differentiation, and apoptosis.
Nehleh Zarei Fard, Tahereh Talaei-Khozani, Soghra Bahmanpour, Tahereh Esmaeilpour   +3 more
doaj  

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

Glia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson, Jorge Botas, Mahyar J. Hedayatpour, Thea Zlatkov, Akdes Serin Harmanci, Christopher J. Yates, Kenneth Nobleza, Roshan Ailani, Adam C. Adler, Farrah Kheradmand, Hyun Kyoung Lee, Benjamin Deneen, Hyun‐Hwan Jeong, Arvind Chandrakantan   +13 more
wiley   +1 more source

Additional file 1: Figure S1. of BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells

, 2017
Negative correlation between Bmp4 and miR-200 family members in murine lung adenocarcinoma cells. Figure S2. Negative correlation between BMP4 and miR-200 family members in human lung adenocarcinomas. Figure S3.
Jeong Kim (3402836), Jonathan Kurie (171087), Young-Ho Ahn (419959)   +2 more
core   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, Volume 6, Issue 11, Page 473-489, November 2026.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, Volume 22, Issue 62, 6 November 2026.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

The effect of BMP4 treatment on iPS cells during corneal epithelial differentiation by the SDIA method.

, 2013
(A, B) 0.5 µM BMP4 was added during the first 2 weeks of differentiation by the SDIA method. Triple immunostaining showed that BMP4 treatment inhibited corneal epithelial induction from both iPS cell lines (K12: red, Pax6: green, K14: blue).
Yukio Nakamura (39120), Tsuyoshi Fujioka (142566), Motokazu Tsujikawa (1588), Kohji Nishida (133839), Yuki Ishikawa (50437), Hiroyuki Miyoshi (127876), Masayuki Yamato (111443), Ryuhei Hayashi (306060), Kuniko Takashiba (306063), Miyuki Ito (306061), Tomofumi Kageyama (306062)   +10 more
core   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, Volume 293, Issue 21, Page 6444-6466, November 2026.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

BMP4 Gene [PDF]

, 2020
openaire   +1 more source

PIH1D2 Loss‐of‐Function Directs Ciliary and Cell Cycle Defects Resulting in Left Isomerism With or Without Biliary Atresia

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background & Aims Laterality disorders are rare congenital conditions caused by disruption of left–right embryonic patterning, often associated with ciliary dysfunction. Despite the identification of numerous causative genes, the molecular basis remains unresolved in many patients.
Alina Kurolap, Chofit Chai Gadot, Adel Shalata, Orly Eshach Adiv, Yam Amir, Bar Levy Lando, Florian Stehling, Tova Hershkovitz, Khaled Osman, Clair Habib, Hila Mintz, Ran Steinberg, Amit Hochberg, Uri Hamiel, Adi Mory, Daphna Marom, Sandra von Hardenberg, Amihood Singer, Bernd Auber, Hagit Baris Feldman   +19 more
wiley   +1 more source

Overexpression of Bmp4 induces microphthalmia by disrupting embryonic neural retina

Neurobiology of Disease
Microphthalmia, mostly an autosomal dominant disorder, is a worldwide severe congenital ocular malformation that causes visual impairment. Our investigation unveiled a total of 30 genes associated with microphthalmia.
Baige Li, Zeyuan Pu, Keren Liao, Yuxin Du, Gao Tan, Scott Nawy, Shiqiang Gao, Yin Shen   +7 more
doaj   +1 more source