Results 121 to 130 of about 32,745 (240)

An Integrative Multi‐Omic Biomarker Panel Distinguishes Hepatocellular Carcinoma From Chronic Liver Disease in HBV‐Predominant Populations

Hepatology Research, EarlyView.
ABSTRACT Aim DNA methylation is a promising diagnostic biomarker for various cancers including hepatocellular carcinoma (HCC). We aimed to identify aberrant DNA methylation and protein alterations via integrated approaches and develop a highly predictive biomarker panel for blood‐based discrimination of HCC from non‐HCC chronic liver disease (CLD) in ...
Hao Zhuang, Xiaopei Hao, Tingting Zhang, Deqiang Li, Guanghao Li, Zhongyi Li, Yuanlin Xu, Shuaiya Ma, Xiangjun Qian, Bo Meng, Xianzhou Zhang, Tiantian Zheng, Feng Han, Hao Wang, Yongmei Li, Nanmu Yang   +15 more
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

BMP4 expression in the adult rat brain [PDF]

雑誌掲載タイトル：Bone morphogenetic protein-4 expression in the adult rat brainBone morphogenetic protein-4 (BMP4) is a member of the transforming growth factor β (TGF- β) superfamily and plays important roles in multiple biological events.
Wang, Cong, Sato, Kohji, Mikawa, Sumiko
core   +2 more sources

Effects of Different Doses of Bone Morphogenetic Protein 4 on Viability and Proliferation Rates of Mouse Embryonic Stem Cells [PDF]

Cell Journal, 2009
Objective: In this study, we examined the effect of different doses of bone morphogeneticprotein 4 (BMP4) on CCE mouse embryonic stem cells (ESCs) viability andproliferation rates in order to improve the outcome of induction processes and make asystem ...
Zohreh Makoolati, Mansoureh Movahedin, Mehdi Forouzandeh-Moghadam   +2 more
doaj  

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

BMP4 dose dictates lineage specification bias in human periodontal ligament stem cells

Frontiers in Bioengineering and Biotechnology
IntroductionPeriodontal ligament stem cells (PDLSCs) represent a promising therapeutic cell source for regenerating periodontal tissues impaired by disease.
Yihong Li, Yihong Li, Qinghuang Tang, Liwen Li, Chensheng Lin, Minhui Guo, Yanding Zhang, Fuhua Yan, Minkui Lin, Minkui Lin   +9 more
doaj   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

The Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass, Kathryn Wolton, Amanda N. Sferruzzi‐Perri   +2 more
wiley   +1 more source

Dullard does not affect BMP4 signalling.

, 2013
(A–A′′) The expression pattern of p-Smads in the proximal epiblast and adjacent extraembryonic ectoderm of the E6.75 Dullard−/− embryo was similar to that in Dullard +/− embryos (A, whole embryo bright-field view; A′, immunofluorescence image; A ...
Kazuki Nakao (366685), Akihiro Nakane (385052), Yasuka L. Yamaguchi (385053), Takeshi Terabayashi (97375), Patrick P. L. Tam (385055), Makoto Asashima (127940), Takaya Abe (106442), Ryuichi Nishinakamura (154253), Satomi S. Tanaka (385051), Kirsten A. Steiner (385054)   +9 more
core   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source