Results 151 to 160 of about 52,292 (275)
Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
Genes & Development, 1999 In many organisms the allocation of primordial germ cells (PGCs) is determined by the inheritance of maternal factors deposited in the egg. However, in mammals, inductive cell interactions are required around gastrulation to establish the germ line. Here,
K. Lawson +7 more
semanticscholar +1 more source
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
The FEBS Journal, EarlyView.PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Biglycan : a multivalent proteoglycan providing structure and signals [PDF]
, 2013 Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Năstase, Mădălina-Viviana +2 more
core
Cells, 2019 Dendritic cells and macrophages are common components of the tumour immune microenvironment and can contribute to immune suppression in both solid and haematological cancers.
Jaris Valencia +6 more
semanticscholar +1 more source
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Objective(s) Yes‐Associated Protein (YAP) is a critical regulator of cell proliferation and differentiation, having the capacity to convert differentiated cells into somatic stem cells in several contexts. Here we investigate the plasticity of adult mouse dental epithelial cells by testing the effects of ectopic YAP activation in dental ...
Zhiyue Zhang +4 more
wiley +1 more source
The role of BMP4 signaling in trophoblast emergence from pluripotency
Cellular and Molecular Life Sciences, 2022 R. Roberts +5 more
semanticscholar +1 more source
European Respiratory Journal, 2019 Airway remodelling in chronic obstructive pulmonary disease (COPD) originates, in part, from smoking-induced changes in airway basal stem/progenitor cells (BCs).
W. Zuo +8 more
semanticscholar +1 more source
Periodontology 2000, EarlyView.Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
Effects of Different Doses of Bone Morphogenetic Protein 4 on Viability and Proliferation Rates of Mouse Embryonic Stem Cells [PDF]
Cell Journal, 2009 Objective: In this study, we examined the effect of different doses of bone morphogeneticprotein 4 (BMP4) on CCE mouse embryonic stem cells (ESCs) viability andproliferation rates in order to improve the outcome of induction processes and make asystem ...
Zohreh Makoolati +2 more
doaj
An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud.
PLoS ONE, 2012 To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified a regulatory region located ∼
Dolrudee Jumlongras +12 more
doaj +1 more source