Results 61 to 70 of about 57,317 (271)

BNCC e a Carta da Terra

Revista de Educação Popular, 2021
Este artigo tem como objetivo discutir a Base Nacional Comum Curricular (BNCC) para lançar luz sobre como são abordados os temas relacionados aos debates atuais sobre a sustentabilidade da vida no planeta nos cinco primeiros anos do ensino fundamental ...
Elisabete Ferreira Esteves Campos
doaj   +1 more source

BNCC

Revista Espaço do Currículo
O objetivo geral deste artigo consiste em investigar como ocorreram as modificações realizadas na disciplina de Geografia, nos anos finais do Ensino Fundamental, mediante a implementação da BNCC, de acordo com a percepção do professor desse componente curricular e do professor PCA que atuam em uma escola estadual do município de Alegre, no Estado do ...
Jane de Oliveira Rezende, Andreia Weiss
openaire   +1 more source

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Aparelhos privados de hegemonia e efetivação da base nacional comum curricular em redes públicas municipais de ensino do Paraná

Revista de estudios teóricos y epistemológicos en política educativa
Este artigo contempla o processo de implementação da Base Nacional Comum Curricular (BNCC) em redes públicas municipais de ensino do Paraná, com foco nos Aparelhos Privados de Hegemonia (APH), bem como na atuação da Secretaria ...
Jussara de Fátima Ivanski Ruppel, Michelle Fernandes Lima   +1 more
doaj   +1 more source

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

Base Nacional Comum Curricular – BNCC

Revista Acadêmica Licencia&acturas, 2016
O presente artigo visa estabelecer uma reflexão crítica acerca da nova versão da Base Nacional Comum Curricular – BNCC mediante a apresentação de pontos importantes da legislação que trata do currículo e da própria base curricular através de uma revisão bibliográfica dos principais marcos legais educacionais.
Delci Heinle Klein, Marcelo Augusto Fröhlich, Raquel Dilly Konrath   +2 more
openaire   +3 more sources

DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi, Fei Li, Heng Jiang, Lingling Gu, Mengjie Sun, Kunyu Lu, Pianpian Liu, Ruyue Xie, Wenqiang Ma, Meijuan Zheng, Xianwei Wang, Xuefu Wang, Jingjing Cong   +12 more
wiley   +1 more source

BNCC and the Portuguese Language in High School: Perspectives, Interfaces and Human Law

Signum: Estudos da Linguagem, 2021
The article discusses the BNCC for Secondary Education in Portuguese, with regard to the guidelines for the development of teaching material in line with the National Program for Education in Human Rights (PNDH) in an attempt to think about teaching ...
Rosana Helena Nunes, Kleber Aparecido da Silva   +1 more
doaj   +1 more source

New results on the genetic cryptanalysis of TEA and reduced-round versions of XTEA [PDF]

, 2004
Congress on Evolutionary Computation. Portland, USA, 19-23 June 2004Recently, a simple way of creating very efficient distinguishers for cryptographic primitives such as block ciphers or hash functions, was presented by the authors.
Hernández, Julio C., Isasi, Pedro
core   +4 more sources