Results 61 to 70 of about 2,812 (182)

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, Volume 7, Issue 4, August 2026.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

As Vozes de Professores-Pesquisadores do Campo da Educação Ambiental sobre a Base Nacional Comum Curricular (BNCC): Educação Infantil ao Ensino Fundamental

Ciência & Educação
Resumo: A pesquisa qualitativa que balizou a produção desse artigo objetivou categorizar as vozes de professores-pesquisadores do campo da educação ambiental sobre a Base Nacional Comum Curricular (BNCC), por meio de entrevista semiestruturada e da ...
Silvana do Nascimento Silva, Carlos Frederico Bernardo Loureiro   +1 more
doaj   +1 more source

ESPORTE, LAZER E BNCC

Corpoconsciência, 2021
Esse estudo propõe a busca de aproximações do esporte dentro da Base Nacional Comum Curricular (BNCC) em uma perspectiva do contexto do lazer. A BNCC foi construída com uma visão de formação dos sujeitos voltados para atender o mercado de trabalho que tenciona com visão de esporte na perspectiva de uma educação para o lazer. Como percurso metodológico,
openaire   +2 more sources

Conjunctival Sac‐Derived Lactobacillus mucosae MM‐1 Metabolite Indole‐3‐Lactic Acid Attenuates Lens‐Induced Myopia in Mice via AHR Activation and TGF‐β/Smad Inhibition

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
This study proposes a ‘conjunctival sac microecology‐metabolite‐scleral remodelling’ regulatory axis, highlighting the potential role of conjunctival sac microbiota in maintaining ocular surface health and regulating lens‐induced myopia in mice, providing an important theoretical foundation for the development of microbiome‐based interventions for ...
Yanqing Li, Qiuyu Wu, Xilong Zhang, Luchuan Liu, Leiping Ding, Jingjing Xu, Chiwen Cheng, Yangyang Peng, Kang Yu, Wen Yao, Yijie Pi, Jiale Li, Di Wu, Jing Wei, Yifeng Yu, Tingtao Chen   +15 more
wiley   +1 more source

BNCC à venda

Áskesis - Revista des discentes do Programa de Pós-Graduação em Sociologia da UFSCar
O estudo aborda três fatores que comprovam a inautenticidade da Base Nacional Comum Curricular – BNCC, tendo como elementos, o Golpe de 2016 que provocou uma crise política nacional; o interesse do capital na relação com os setores privados e a ausência de participação popular que excluiu professores e pesquisadores do debate laboral.
Fábio José Brito dos Santos, Jonatha Pereira Bugarim   +1 more
openaire   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, Volume 13, Issue 41, 22 July 2026.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

PELOS MEANDROS DA BNCC

Periferia, 2023
Em nossas práticas, enquanto coordenadores de distintos Projetos que desenvolvemos junto a alunos do curso de Licenciatura em Letras da Universidade do Estado do Rio de Janeiro (UERJ), nos vimos diante da necessidade de refletir sobre como e se a Base Nacional Curricular (BNCC) é um documento imprescindível para sustentar o desenvolvimento de nossos ...
Ceres Ferreira Carneiro, Felipe Bastos Mansur   +1 more
openaire   +1 more source

Olfml3 Regulates Microglial Inflammation and Neuronal Injury in Obstructive Sleep Apnea via Cybb‐Mediated TLR4/NF‐κB Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
In obstructive sleep apnea (OSA), intermittent hypoxia (IH) induces downregulation of Olfml3 in microglial cells and inhibits the activation of microglial cells; Low Olfml3 expression leads to increased expression of the downstream gene Cybb; Cybb activates the TLR4/NF‐κB inflammatory pathway, driving microglial M1 polarization and the release of ...
Deqiu Kong, Yaowen Wang, Xianjun Chen, Cihao Hu, Bin Zhang, Xing Chen   +5 more
wiley   +1 more source

BNCC and the Portuguese Language in High School: Perspectives, Interfaces and Human Law

Signum: Estudos da Linguagem, 2021
The article discusses the BNCC for Secondary Education in Portuguese, with regard to the guidelines for the development of teaching material in line with the National Program for Education in Human Rights (PNDH) in an attempt to think about teaching ...
Rosana Helena Nunes, Kleber Aparecido da Silva   +1 more
doaj   +1 more source

Podocyte mPGES‐2 Determines Renal Aging and Contributes to Senile Osteoporosis

Aging Cell, Volume 25, Issue 7, July 2026.
Podocyte mPGES‐2 drives renal aging through PGE2/EP1‐dependent senescence and disrupts renal endocrine support for bone homeostasis. Genetic deletion or pharmacological inhibition of mPGES‐2 protects aged mice from kidney dysfunction and osteoporosis. ABSTRACT Renal aging shortens healthspan and propagates organ dysfunction beyond the kidney, yet its ...
Dandan Zhong, Chang Hao, Mengyue Li, Jing Liu, Zheng Xu, Jianteng Zhou, Lu Zhao, Siyu Ni, Zhenchao Hu, Yue Sun, Yingying Zou, Dong Sun, Hao Guo, Zhanjun Jia, Dong Guo, Jun‐Li Cao, Ying Sun   +16 more
wiley   +1 more source