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INEL BNCT Program Directions with Respect to Clinical Trials of BNCT
1992The Idaho National Engineering Laboratory's Boron Neutron Capture Therapy (INEL/BNCT) Program was initially established in 1984 to provide a new improved, effective treatment for Glioblastoma Multiforme. To address this need, the Program was organized with four goals in mind: (1) develop BNCT as a more effective brain tumor treatment, (2) expand BNCT ...
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2001
Boron-containing nucleosides are attractive agents for BNCT1 because they may be (1) taken up selectively into tumors due to the high mitotic rate of tumor cells vs. normal cells, (2) intracellularly converted to the corresponding nucleotides through phosphorylation by appropriate enzymes such as TK1 or dCK, and (3) possibly incorporated into tumor ...
Jin-Cong Zhuo +3 more
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Boron-containing nucleosides are attractive agents for BNCT1 because they may be (1) taken up selectively into tumors due to the high mitotic rate of tumor cells vs. normal cells, (2) intracellularly converted to the corresponding nucleotides through phosphorylation by appropriate enzymes such as TK1 or dCK, and (3) possibly incorporated into tumor ...
Jin-Cong Zhuo +3 more
openaire +1 more source
Semiconductor Dosimetry in BNCT
2001The problems of neutron and gamma dosimetry in epithermal Boron Neutron Capture Therapy (BNCT) is quite complicated due to the wide epithermal neutron spectra 0.5—10 keV, fast neutron contribution up to 14MeV and photons from the reactor and induced in the phantom due to H(n,γ)H reaction. Furthermore, contributions from high LET products arising from B-
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2001
If BNCT were performed in a single, unique facility and if its science were unique, concepts and terminology specific to this new modality could be developed. However, BNCT is a form of radiation therapy. To benefit from the vast accumulated experience with all types of radiation therapy and to ensure a common understanding and allow a fruitful ...
R. Gahbauer +5 more
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If BNCT were performed in a single, unique facility and if its science were unique, concepts and terminology specific to this new modality could be developed. However, BNCT is a form of radiation therapy. To benefit from the vast accumulated experience with all types of radiation therapy and to ensure a common understanding and allow a fruitful ...
R. Gahbauer +5 more
openaire +1 more source
2000
A phase I BNCT trial in glioblastoma started at the Finnish BNCT facility in May 1999. The aim of the present work was to verify the doses calculated in treatment planning and estimate the whole body dose on the basis of neutron fluence and gamma dose measurements in vivo and in a whole body phantom.
Karila, Johanna +10 more
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A phase I BNCT trial in glioblastoma started at the Finnish BNCT facility in May 1999. The aim of the present work was to verify the doses calculated in treatment planning and estimate the whole body dose on the basis of neutron fluence and gamma dose measurements in vivo and in a whole body phantom.
Karila, Johanna +10 more
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A Review of Planned, Ongoing Clinical Studies and Recent Development of BNCT in Mainland of China
Cancers, 2023Yuan-Hao Liu +2 more
exaly
Radiobiological features of BNCT.
1998INFN/TC 98 ...
PORCIANI, SAURO, BECCIOLINI, ALDO
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Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2023
exaly
exaly