Results 61 to 70 of about 2,067 (154)

Functionalizing Injectable Hydrogels with Cobalt‐Based Metallacarboranes for Targeted Delivery in Triple‐Negative Breast Cancer

ChemBioChem, Volume 26, Issue 21, November 8, 2025.
This study reports a biocompatible HA–lysine hydrogel loaded with cobalt metallacarborane (CoSAN) for targeted release into triple‐negative breast cancer cells. The system maintains CoSAN cytotoxicity, as confirmed by cell assays and imaging, representing an attractive approach toward a localised TNBC treatment.
Neville Murphy, Roberto González‐Gómez, Nivethitha Ashok, Enda O’Connell, Howard Fearnhead, William J. Tipping, Karen Faulds, Wenming Tong, Abhay Pandit, Róisín M. Dwyer, Duncan Graham, Pau Farràs   +11 more
wiley   +1 more source

Investigations into the characterization, degradation, and applications of biodegradable polymers by mass spectrometry

Mass Spectrometry Reviews, Volume 44, Issue 6, Page 947-988, November/December 2025.
Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli, Melania Leanza, Marco Rapisarda   +2 more
wiley   +1 more source

Maxwell Spectrum as a Parameter to Verify the Dose in Brain Cancer (Glioblastoma) by Boron Neutron Capture Therapy (BNCT) using Monte Carlo Method

Brazilian Journal of Radiation Sciences
To evaluate the efficiency of neutron capture therapy (BNCT) treatment in glioblastoma multiforme, it is necessary to evaluate the impact of the neutron beam on the tumor cell and find better results so that BNCT treatment is viable.
Otto Haubrich, Domingos D'Oliveira Cardoso, Marcos Paulo Cavaliere de Medeiros   +2 more
doaj   +1 more source

Boronated Compounds for Imaging Guided BNCT Applications

Anti-Cancer Agents in Medicinal Chemistry, 2012
Boron neutron capture therapy (BNCT) is based on the capture of thermal neutrons by boron 10 ((10)B) nuclei that have been selectively delivered to tumor cells. The amount of 10-30 μg of boron for g of tumor mass is needed to attain an acceptable therapeutic advantage.
GENINATTI CRICH, Simonetta, DEAGOSTINO, Annamaria, TOPPINO, Antonio, ALBERTI, DIEGO, VENTURELLO, Paolo, AIME, Silvio   +5 more
openaire   +3 more sources

Recent research progress of BNCT treatment planning system

Nuclear Engineering and Technology
Boron neutron capture therapy (BNCT) is a type of radiation therapy that can selectively kill tumor cells. It is necessary to design a suitable treatment plan and assess its efficacy based on the actual situation of the patient before BNCT treatment. The
Zhaotong Wang, Qi Zheng, Bo Wang, Zhifeng Li, Jie Li, Sheng Wang, Hongbing Song, Baofeng Wang   +7 more
doaj   +1 more source

Development of an integrated Monte Carlo model for glioblastoma multiforme treated with boron neutron capture therapy

Scientific Reports, 2017
Glioblastomas (GBM) are notorious for their high fatality rate. Boron Neutron Capture Therapy (BNCT) being a biochemically targeted type of radiotherapy is a potent modality for GBM.
Leyla Moghaddasi, Eva Bezak
doaj   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

Preliminary outcomes of boron neutron capture therapy for head and neck cancers as a treatment covered by public health insurance system in Japan: Real‐world experiences over a 2‐year period

Cancer Medicine
Purpose Since June 2020, boron neutron capture therapy (BNCT) has been a health care service covered by health insurance in Japan to treat locally advanced or recurrent unresectable head and neck cancers.
Satoshi Takeno, Yuki Yoshino, Teruhito Aihara, Masaaki Higashino, Yasukazu Kanai, Naonori Hu, Ryo Kakino, Ryo Kawata, Keiji Nihei, Koji Ono   +9 more
doaj   +1 more source

Development of a New Image Reconstruction Method Using Bayesian Estimation with Limited View-Angle Projection Data for BNCT-SPECT

Applied Sciences
Boron Neutron Capture Therapy (BNCT) is an emerging radiation treatment for cancer, and its challenges are being explored. Systems capable of capturing real-time observations of this treatment’s effectiveness, particularly BNCT-SPECT methods that measure
Fan Lu, Haruka Inamoto, Shuto Takeishi, Shingo Tamaki, Sachie Kusaka, Isao Murata   +5 more
doaj   +1 more source

Comparison of lifetime attributable risk of post-irradiation secondary cancer of boron neutron capture therapy, proton beam therapy, and X-ray therapy for pediatric and adolescent and young adult patients

Clinical and Translational Radiation Oncology
Background and purpose: This study aimed to compare the post-irradiation secondary cancer rates of boron neutron capture therapy (BNCT), proton beam therapy (PBT), and X-ray therapy (XT) in pediatric and Adolescent and Young Adult (AYA) patients with ...
Shunsuke Suzuki, Shintaro Shiba, Hiroki Tanaka, Masashi Yamanaka, Kazuki Matsumoto, Koichi Tokuuye, Motoko Omura   +6 more
doaj   +1 more source