Results 11 to 20 of about 1,031 (131)

Generation of Anti-Boa Immunoglobulin Antibodies for Serodiagnostic Applications, and Their Use to Detect Anti-Reptarenavirus Antibodies in Boa Constrictor. [PDF]

PLoS ONE, 2016
Immunoglobulins (Igs), the key effectors of the adaptive immune system, mediate the specific recognition of foreign structures, i.e. antigens. In mammals, IgM production commonly precedes the production of IgG in the response to an infection.
Yegor Korzyukov, Udo Hetzel, Anja Kipar, Olli Vapalahti, Jussi Hepojoki   +4 more
doaj   +5 more sources

Arenavirus Coinfections Are Common in Snakes with Boid Inclusion Body Disease [PDF]

Journal of Virology, 2015
ABSTRACT Recently, novel arenaviruses were found in snakes with boid inclusion body disease (BIBD); these form the new genus Reptarenavirus within the family Arenaviridae . We used next-generation sequencing and de novo sequence assembly to investigate ...
Kipar A., Hepojoki J., Vapalahti O., Salmenpera P., Sironen T., Hetzel U., Korzyukov Y., Kipar A., Hepojoki J., Vapalahti O., Salmenpera P., Sironen T., Hetzel U., Korzyukov Y.   +13 more
openaire   +3 more sources

Replication of Boid Inclusion Body Disease-Associated Arenaviruses Is Temperature Sensitive in both Boid and Mammalian Cells [PDF]

Journal of Virology, 2015
ABSTRACT Boid inclusion body disease (BIDB) is a fatal disease of boid snakes, the etiology of which has only recently been revealed following the identification of several novel arenaviruses in diseased snakes. BIBD-associated arenaviruses (BIBDAV) are genetically divergent from the classical Old and New World arenaviruses and ...
Hepojoki, J, Kipar, A, Korzyukov, Y, Bell-Sakyi, L, Vapalahti, O, Hetzel, U   +5 more
openaire   +4 more sources

Identification of Reptarenaviruses, Hartmaniviruses, and a Novel Chuvirus in Captive Native Brazilian Boa Constrictors with Boid Inclusion Body Disease [PDF]

Journal of Virology, 2020
Boid inclusion body disease (BIBD), caused by reptarenavirus infection, affects captive snake populations worldwide, but the reservoir hosts of reptarenaviruses remain unknown. Here, we report the identification of novel reptarenaviruses, hartmaniviruses, and a chuvirus in captive Brazilian boas with BIBD.
Argenta, Fernando Froner, Hepojoki, Jussi, Smura, Teemu, Szirovicza, Leonora, Hammerschmitt, Márcia Elisa, Driemeier, David, Kipar, Anja, Hetzel, Udo   +7 more
europepmc   +5 more sources

Molecular characterization of a reptarenavirus detected in a Colombian Red-Tailed Boa (Boa constrictor imperator) [PDF]

Virology Journal, 2023
The global decline in biodiversity is a matter of great concern for members of the class Reptilia. Reptarenaviruses infect snakes, and have been linked to various clinical conditions, such as Boid Inclusion Body Disease (BIBD) in snakes belonging to the ...
Mohamed A. Abouelkhair, Ashkan Roozitalab, Ola K. Elsakhawy   +2 more
doaj   +2 more sources

A subpopulation of arenavirus nucleoprotein localizes to mitochondria [PDF]

Scientific Reports, 2021
Viruses need cells for their replication and, therefore, ways to hijack cellular functions. Mitochondria play fundamental roles within the cell in metabolism, immunity and regulation of homeostasis due to which some viruses aim to alter mitochondrial ...
Francesca Baggio, Udo Hetzel, Lisbeth Nufer, Anja Kipar, Jussi Hepojoki   +4 more
doaj   +2 more sources

Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease [PDF]

Journal of Virology, 2013
ABSTRACT Boid inclusion body disease (BIBD) is a progressive, usually fatal disease of constrictor snakes, characterized by cytoplasmic inclusion bodies (IB) in a wide range of cell types. To identify the causative agent of the disease, we established cell cultures from BIBD-positive and -negative boa constrictors.
Patjas Aino, Kipar Anja, Vaheri Antti, Hepojoki Jussi, Liljeroos Lassi, Vapalahti Olli, Laurinmäki Pasi, Butcher Sarah J., Sironen Tarja, Hetzel Udo, Patjas Aino, Kipar Anja, Vaheri Antti, Hepojoki Jussi, Liljeroos Lassi, Vapalahti Olli, Laurinmäki Pasi, Butcher Sarah J., Sironen Tarja, Hetzel Udo   +19 more
openaire   +5 more sources

Virtopsy of a gravid Boa constrictor using computed tomography and magnetic resonance imaging [PDF]

Veterinary and Animal Science, 2020
: This article presents radiologic examinations of a deeply sedated Boa constrictor with boid inclusion body disease (BIBD) as an adjunction to the subsequent necropsy. This method is known as virtopsy. The Boa constrictor in the present case was gravid.
Dominic Gascho, Udo Hetzel, Nicole Schmid, Rosa M Martinez, Michael J Thali, Henning Richter   +5 more
doaj   +2 more sources

Characterization of Haartman Institute snake virus-1 (HISV-1) and HISV-like viruses-The representatives of genus Hartmanivirus, family Arenaviridae. [PDF]

PLoS Pathogens, 2018
The family Arenaviridae comprises three genera, Mammarenavirus, Reptarenavirus and the most recently added Hartmanivirus. Arenaviruses have a bisegmented genome with ambisense coding strategy.
Jussi Hepojoki, Satu Hepojoki, Teemu Smura, Leonóra Szirovicza, Eva Dervas, Barbara Prähauser, Lisbeth Nufer, Elisabeth M Schraner, Olli Vapalahti, Anja Kipar, Udo Hetzel   +10 more
doaj   +2 more sources

Viruses in reptiles [PDF]

Veterinary Research, 2011
The etiology of reptilian viral diseases can be attributed to a wide range of viruses occurring across different genera and families. Thirty to forty years ago, studies of viruses in reptiles focused mainly on the zoonotic potential of arboviruses in ...
Ariel Ellen
doaj   +2 more sources