Results 31 to 40 of about 606,113 (264)

Roles of Gut Microbiome in Bone Homeostasis and Its Relationship with Bone-Related Diseases. [PDF]

Biology (Basel), 2022
The extended microbial genome—the gut microbiome (GM)—plays a significant role in host health and disease. It is able to influence a number of physiological functions. During dysbiosis, GM is associated with the development of various chronic diseases with impaired bone quality.
Zemanova N, Omelka R, Mondockova V, Kovacova V, Martiniakova M.   +4 more
europepmc   +4 more sources

Vibration Therapy for Cancer-Related Bone Diseases

Vibration, 2023
Patients undergoing cancer treatments and/or suffering from metastatic bone lesions experience various skeletal-related events (SREs), substantially reducing functional independence and quality of life.
Xin Song, Amel Sassi, Kimberly Seaman, Chun-Yu Lin, Lidan You   +4 more
doaj   +1 more source

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone-Related Diseases. [PDF]

Cell Prolif
ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems. Conventional therapeutic approaches, including anti‐resorptive drugs and surgical interventions, face limitations such as long‐term medication
Long X, Tan D, Tao Q, Ye Q, Ye L, Li Q, Xiao J.   +6 more
europepmc   +3 more sources

Aptamer-functionalized biomaterials for bone-related diseases therapy

Cell Biomaterials
Qi Li, Mingzhu Zhang
openalex   +2 more sources

Essential role of the metabolite α-ketoglutarate in bone tissue and bone-related diseases. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Bone metabolism in bone tissue is constantly maintained in a state of dynamic equilibrium. The mass of bone and joint tissues is determined by both bone formation and bone resorption. It is hypothesized that disrupted metabolic balance leads to osteoporosis, osteoarthritis, rheumatoid arthritis, and bone tumors.
Wu Z, Guan Y, Chen Q, Song R, Xie J, Zhang X, Wang Y, Chen Q, Chen X.   +8 more
europepmc   +3 more sources

Bone-Related Markers of Cardiovascular Disease

European Medical Journal, 2020
A growing body of evidence describes a strict relationship between bone and cardiovascular disease (CVD), with several physiological and pharmacological implications. Advances in our understanding of the pathophysiology of osteoporosis and vascular calcifications indicate that these two processes share common pathogenetic mechanisms, suggesting the ...
Ernesto Maddaloni, Carmen Mignogna, Lucia Coraggio, Michela Guida, Raffaella Buzzetti   +4 more
openalex   +2 more sources

Obesity and Bone Health: A Complex Link

Frontiers in Cell and Developmental Biology, 2020
So far, the connections between obesity and skeleton have been extensively explored, but the results are inconsistent. Obesity is thought to affect bone health through a variety of mechanisms, including body weight, fat volume, bone formation/resorption,
Jing Hou, Chen He, Wenzhen He, Mi Yang, Mi Yang, Mi Yang, Xianghang Luo, Xianghang Luo, Xianghang Luo, Changjun Li, Changjun Li, Changjun Li   +11 more
doaj   +1 more source

Role of irisin in bone diseases

Frontiers in Endocrinology, 2023
Bone diseases are common among middle-aged and elderly people, and harm to activities of daily living (ADL) and quality of life (QOL) for patients. It is crucial to search for key regulatory factors associated with the development of bone diseases and ...
Ruobing Zhao, Yan Chen, Dongxue Wang, Chunyu Zhang, Henan Song, Guoxin Ni   +5 more
doaj   +1 more source

Mitophagy—A New Target of Bone Disease

Biomolecules, 2022
Bone diseases are usually caused by abnormal metabolism and death of cells in bones, including osteoblasts, osteoclasts, osteocytes, chondrocytes, and bone marrow mesenchymal stem cells.
Zhipeng Zeng, Xuchang Zhou, Yan Wang, Hong Cao, Jianmin Guo, Ping Wang, Yajing Yang, Yan Wang   +7 more
doaj   +1 more source

Minimal residual disease detection by next-generation sequencing in multiple myeloma: Promise and challenges for response-adapted therapy

Frontiers in Oncology, 2022
Assessment of minimal residual disease (MRD) is becoming a standard diagnostic tool for curable hematological malignancies such as chronic and acute myeloid leukemia. Multiple myeloma (MM) remains an incurable disease, as a major portion of patients even
Valeria Ferla, Elena Antonini, Tommaso Perini, Tommaso Perini, Francesca Farina, Serena Masottini, Simona Malato, Sarah Marktel, Maria Teresa Lupo Stanghellini, Cristina Tresoldi, Fabio Ciceri, Fabio Ciceri, Magda Marcatti   +12 more
doaj   +1 more source