Results 11 to 20 of about 606,113 (264)

Th17 and Treg Cells in Bone Related Diseases [PDF]

Clinical and Developmental Immunology, 2013
Bone-related diseases share the process of immune response that targets bone tissue and bone marrow and then induce adverse effects on structure and function.
Min Wang, Tian Tian, Shuang Yu, Na He, Daoxin Ma   +4 more
doaj   +6 more sources

Research progress of circRNAs in bone-related diseases [PDF]

Frontiers in Oncology
Circular RNAs (circRNAs) are non-coding RNAs that exist naturally in various eukaryotic organisms. The majority of circRNAs are produced through the splicing of exons, although there are a limited number that are generated through the circularization of ...
Xianming Hua, Lingfeng Yu, Hao Zhu, Yan Zhu, Gentao Fan, Guangxin Zhou, Guangxin Zhou, Guangxin Zhou   +7 more
doaj   +4 more sources

Ferroptosis and its implications in bone-related diseases [PDF]

PeerJ
Ferroptosis, a recently recognized form of regulated cell death (RCD) characterized by iron-dependent lipid peroxide accumulation, has emerged as a noteworthy regulator in various bone-related diseases, including osteoporosis (OP), osteoarthritis (OA ...
Zihao Wang, Qiupeng Yan, Zhen Wang, Zunguo Hu, Chenchen Wang, Xue Zhang, Xueshuai Gao, Xue Bai, Xiaosu Chen, Lingyun Zhang, Danyue Lv, Huancai Liu, Yanchun Chen   +12 more
doaj   +5 more sources

Functions and Clinical Significance of Super-Enhancers in Bone-Related Diseases [PDF]

Frontiers in Cell and Developmental Biology, 2020
Super-enhancers (SEs) are a large cluster of cis-regulatory DNA elements that contain many binding motifs, which master transcription factors and cofactors bind to with high density.
Jian Qu, Jian Qu, Zhanbo Ouyang, Zhanbo Ouyang, Wenqiang Wu, Guohua Li, Guohua Li, Jiaojiao Wang, Jiaojiao Wang, Qiong Lu, Qiong Lu, Zhihong Li, Zhihong Li   +12 more
doaj   +5 more sources

Insight into the roles of melatonin in bone tissue and bone‑related diseases (Review). [PDF]

Int J Mol Med, 2021
Bone‑related diseases comprise a large group of common diseases, including fractures, osteoporosis and osteoarthritis (OA), which affect a large number of individuals, particularly the elderly. The progressive destruction and loss of alveolar bone caused by periodontitis is a specific type of bone loss, which has a high incidence and markedly reduces ...
Lu X, Yu S, Chen G, Zheng W, Peng J, Huang X, Chen L.   +6 more
europepmc   +5 more sources

Role of apoptosis in pathogenesis and treatment of bone-related diseases. [PDF]

J Orthop Surg Res, 2015
In this article, bone cells and their intercellular communications have been reviewed. Gap junctions and hemichannels are the main routes of interactions in bone tissue. They play a substantial role in survival and cell death, since pro-apoptotic signals can propagate through them.
Mollazadeh S, Fazly Bazzaz BS, Kerachian MA.   +2 more
europepmc   +6 more sources

Oral microbiome, periodontal disease and systemic bone-related diseases in the era of homeostatic medicine [PDF]

Journal of Advanced Research
Background: Homeostasis is a state of self-regulation and dynamic equilibrium, maintaining the good physiological functions of each system in living organisms.
Weiqi Hu, Shuoling Chen, Xianghui Zou, Yan Chen, Jiayu Luo, Peiliang Zhong, Dandan Ma   +6 more
doaj   +4 more sources

Impact of Quercetin on Bone-Related Diseases

Applied Sciences
Quercetin (QE) is a widely distributed dietary flavonol with antioxidant and anti-inflammatory properties that has attracted interest as a modulator of bone remodeling and osteoporosis-related bone loss.
Paweł Polak, Magdalena Dragan, Antoni Wojciech Oniszczuk, Emilia Skurko, Kamila Kasprzak-Drozd, Przemysław Niziński, Anna Oniszczuk, Karolina Wojtunik-Kulesza   +7 more
doaj   +2 more sources

Microbiota-bone axis in ageing-related bone diseases

Frontiers in Endocrinology
Bone homeostasis in physiology depends on the balance between bone formation and resorption, and in pathology, this homeostasis is susceptible to disruption by different influences, especially under ageing condition. Gut microbiota has been recognized as
Liangxuan Fu, Peilin Zhang, Yicheng Wang, Xiaonan Liu   +3 more
doaj   +3 more sources

Nanomaterial-assisted theranosis of bone diseases

Bioactive Materials, 2023
Bone-related diseases refer to a group of skeletal disorders that are characterized by bone and cartilage destruction. Conventional approaches can regulate bone homeostasis to a certain extent.
Kai Zheng, Jiaxiang Bai, Huilin Yang, Yaozeng Xu, Guoqing Pan, Huaiyu Wang, Dechun Geng   +6 more
doaj   +3 more sources