Therapeutic application of hydrogels for bone-related diseases [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Bone-related diseases caused by trauma, infection, and aging affect people’s health and quality of life. The prevalence of bone-related diseases has been increasing yearly in recent years.
Xiyu Liu +7 more
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Visualization Analysis of Small Extracellular Vesicles in the Application of Bone-Related Diseases [PDF]
CellsSmall extracellular vesicles were shown to have similar functional roles to their parent cells without the defect of potential tumorigenicity, which made them a great candidate for regenerative medicine.
Xinjiani Chen +8 more
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GNAS locus: bone related diseases and mouse models [PDF]
Frontiers in Endocrinology, 2023 GNASis a complex locus characterized by multiple transcripts and an imprinting effect. It orchestrates a variety of physiological processes via numerous signaling pathways.
Wan Yang +6 more
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Role of Exosomal Non-Coding RNAs in Bone-Related Diseases [PDF]
Frontiers in Cell and Developmental Biology, 2021 Bone-related diseases seriously affect the lives of patients and carry a heavy economic burden on society. Treatment methods cannot meet the diverse clinical needs of affected patients.
Hang Li +14 more
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Reactive Oxygen Species (ROS)-Responsive Biomaterials for the Treatment of Bone-Related Diseases [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Reactive oxygen species (ROS) are the key signaling molecules in many physiological signs of progress and are associated with almost all diseases, such as atherosclerosis, aging, and cancer.
Xiaoxiang Ren +6 more
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Advances in the Study of Exosomes as Drug Delivery Systems for Bone-Related Diseases [PDF]
Pharmaceutics, 2023 Bone-related diseases are major problems and heavy burdens faced by modern society. Current clinical approaches for the treatment of these pathological conditions often lead to complications and have limited therapeutic efficacy.
Jiawen Huang +9 more
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Stat3 Signaling Pathway: A Future Therapeutic Target for Bone-Related Diseases [PDF]
Frontiers in Pharmacology, 2022 Signal transducer and activator of transcription 3 (Stat3) is activated by phosphorylation and translocated to the nucleus to participate in the transcriptional regulation of DNA.
Jiadong Li +6 more
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Targeting Ferroptosis in Bone-Related Diseases: Facts and Perspectives [PDF]
Journal of Inflammation Research, 2023 Haoran Chen,1,2,* Zhongyu Han,2,* Yi Wang,1,* Junyan Su,3 Yumeng Lin,4 Xuhua Cheng,1 Wen Liu,1 Jingyu He,5 Yiyue Fan,6 Liuyan Chen,2 Houdong Zuo1 1Department of Orthopaedics, Chengdu Xinhua Hospital, Chengdu, 610000, People’s Republic of ...
Chen H +10 more
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Macropinocytosis fuels osteoclast differentiation in bone-related diseases [PDF]
Journal of Orthopaedic TranslationObjective: Multinucleated osteoclasts are the principal specialised cells responsible for bone resorption, but osteoclastogenesis, the formation of osteoclasts, entails substantial nutrient and bioenergetic demands.
Mengqin Gu +7 more
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Mesenchymal Stem Cell-Derived Extracellular Vesicles in Bone-Related Diseases: Intercellular Communication Messengers and Therapeutic Engineering Protagonists [PDF]
International Journal of NanomedicineYanyi Wang,1,2,* Juan Wen,1– 3,* Tong Lu,1,2 Wei Han,2,4 Kai Jiao,5 Huang Li1,2 1Department of Orthodontics, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing ...
Wang Y, Wen J, Lu T, Han W, Jiao K, Li H
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