Results 101 to 110 of about 6,066,361 (406)
Forum: Qualitative Social Research, 2007 This article reconstructs epistemology in the tradition of Gaston BACHELARD as one of the main foundations of the methodology of FOUCAULTian discourse analysis.
Rainer Diaz-Bone
doaj
A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling [PDF]
, 2010 In this study, we investigated a clinically relevant model of in vivo ectopic bone formation utilizing human periosteum derived cells (HPDCs) seeded in a Collagraft carrier and explored the mechanisms by which this process is driven.
Eyckmans, Jeroen +3 more
core +1 more source
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Developing Foucault's Discourse Analytic Methodology
Forum: Qualitative Social Research, 2006 A methodological position for a FOUCAULTian discourse analysis is presented. A sequence of analytical steps is introduced and an illustrating example is offered.
Rainer Diaz-Bone
doaj
Oncology Reviews, 2017 Bone is a frequent site of metastases and typically indicates a short-term prognosis in cancer patients. Once cancer has spread to the bones it can rarely be cured, but often it can still be treated to slow its growth. The majority of skeletal metastases
F. Macedo +6 more
semanticscholar +1 more source
Micro-CT Characterization of Human Trabecular Bone in Osteogenesis Imperfecta [PDF]
, 2011 Osteogenesis imperfecta (OI) is a genetic syndrome affecting collagen synthesis and assembly. Its symptoms vary widely but commonly include bone fragility, reduced stature, and bone deformity.
Albert, Carolyne +4 more
core +2 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass [PDF]
, 2011 Context: The hormonal factors involved in the regulation of peak bone mass (PBM) in men have not been fully investigated. Apart from gonadal steroids and somatotropic hormones, thyroid hormones are known to affect bone maturation and homeostasis and are ...
Fiers, Tom +6 more
core +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source