Results 61 to 70 of about 4,131,374 (358)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The Performativity of Qualitative Social Research

open access: yesForum: Qualitative Social Research, 2011
Within the last two decades qualitative social research has established itself in most, if not all, of the social sciences. But this emergence has proceeded very differently in institutional and in socio-cognitive aspects.
Rainer Diaz-Bone
doaj  

Penerapan Model Pembelajaran ROAR (Read, Observe, Auditory, Review) Meningkatkan Pemahaman Konsep Siswa

open access: yesIndonesian Journal of Learning Education and Counseling, 2019
The ROAR learning model is learning that gives students the broadest opportunity to develop concepts, pre-existing ideas become new concepts. The concept is built through direct observation because during learning the teacher presents examples of reality
Emmi Azis   +5 more
doaj   +1 more source

Targeting cellular senescence prevents age-related bone loss in mice

open access: yesNature Medicine, 2017
Aging is associated with increased cellular senescence, which is hypothesized to drive the eventual development of multiple comorbidities. Here we investigate a role for senescent cells in age-related bone loss through multiple approaches. In particular,
J. Farr   +17 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Developing the Halal-Tech Maturity Index for Traditional Market MSEs: A Strategy for Value-Digital Integration

open access: yesInferensi Jurnal Penelitian Sosial Keagamaan
This study develops the Halal-Tech Maturity Index (HTMI), a novel composite instrument that integrates halal awareness and digital readiness within traditional market-based micro and small enterprises (MSEs)—an area underexplored in current halal economy
Syaparuddin Razak   +5 more
doaj   +1 more source

3D bioactive composite scaffolds for bone tissue engineering

open access: yesBioactive Materials, 2017
Bone is the second most commonly transplanted tissue worldwide, with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.
G. Turnbull   +7 more
semanticscholar   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Pelatihan Pembuatan Website Desa dengan Media Google Sites

open access: yesMadaniya
Google Sites dibuat agar memudahkan penggunanya walaupun tidak berlatar belakang di bidang teknologi informasi untuk memahami pengoperasiannya dalam waktu singkat sehingga penggunanya dapat mengembangkan website yang sederhana sesuai dengan fungsinya ...
Fahriadi Muhdar   +7 more
doaj   +1 more source

Injectable hydrogels for cartilage and bone tissue engineering

open access: yesBone Research, 2017
Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture ...
Mei Liu   +8 more
semanticscholar   +1 more source

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