Results 61 to 70 of about 10,064,619 (345)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Serum vitamin D levels in girls with central precocious puberty

Pharmaceutical and Biomedical Research, 2018
Precocious puberty can cause several adverse effects on final growth and social behavior in girls. Recent studies showed that low serum level of vitamin D might be associated with precocious puberty.
Mohammadreza Rafati, Daniel Zamanfar, Seyedeh-Nesa RezaeianShiadeh, Fatemeh Faramarzi, Mohsen Aarabi, Hamid Rayati Damavandi   +5 more
doaj  

Automated Distal Radius and Ulna Skeletal Maturity Grading from Hand Radiographs with an Attention Multi-Task Learning Method

Tomography
Background: Assessment of skeletal maturity is a common clinical practice to investigate adolescent growth and endocrine disorders. The distal radius and ulna (DRU) maturity classification is a practical and easy-to-use scheme that was designed for ...
Xiaowei Liu, Rulan Wang, Wenting Jiang, Zhaohua Lu, Ningning Chen, Hongfei Wang   +5 more
doaj   +1 more source

Fully Automated Deep Learning System for Bone Age Assessment

Journal of digital imaging, 2017
Skeletal maturity progresses through discrete phases, a fact that is used routinely in pediatrics where bone age assessments (BAAs) are compared to chronological age in the evaluation of endocrine and metabolic disorders.
Hyunkwang Lee, Shahein H. Tajmir, Jenny Lee, Maurice Zissen, Bethel Ayele Yeshiwas, Tarik K. Alkasab, G. Choy, Synho Do   +7 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Correlación entre las edades cronológica y ósea en pacientes de ortodoncia Correlation between the chronological and bone ages in orthodontics patients

Revista Cubana de Estomatología, 2011
Nos propusimos determinar la edad ósea según sexo y edad cronológica e identificar la relación existente entre las edades cronológica y ósea, en los pacientes estudiados.
Gladia Toledo Mayarí, Rigoberto Otaño Lugo   +1 more
doaj  

Skeletal Maturity in Adolescence: Evaluating Bone Development and Age Metrics

Diagnostics
Background/Objectives: Bone maturation and development are crucial for growth and development, especially in children and adolescents; however, some qualitative methods, such as Greulich & Pyle, do not provide accurate data.
João Pinheiro, Luís Ribeiro, Diana Teixeira, Anabela Ribeiro, Manuel João Coelho-e-Silva   +4 more
doaj   +1 more source

Improving Automated Pediatric Bone Age Estimation Using Ensembles of Models from the 2017 RSNA Machine Learning Challenge.

Radiology: Artificial Intelligence, 2019
Purpose To investigate improvements in performance for automatic bone age estimation that can be gained through model ensembling. Materials and Methods A total of 48 submissions from the 2017 RSNA Pediatric Bone Age Machine Learning Challenge were used.
I. Pan, H. H. Thodberg, S. Halabi, Jayashree Kalpathy-Cramer, D. Larson   +4 more
semanticscholar   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Variant pubertal development in Prader-Willi syndrome: early and slow progression of pubarche with normal age at gonadarche

Frontiers in Endocrinology
IntroductionPrader-Willi syndrome (PWS) is primarily caused by a paternal microdeletion of the 15q11-q13 region, maternal uniparental disomy (mUPD) or unbalanced translocations.
Aneta Kodytková, Petra Dušátková, Shenali Anne Amaratunga, Stanislava Koloušková, Barbora Obermannová, Renata Pomahačová, Štěpánka Průhová, Marta Šnajderová, Zdeněk Šumník, Jiřina Zapletalová, Valerij Semjonov, Jan Lebl   +11 more
doaj   +1 more source