Results 11 to 20 of about 12,008,318 (406)
Bone-immune cell crosstalk: Bone diseases [PDF]
Journal of Immunological Research, 2015 Bone diseases are associated with great morbidity; thus, the understanding of the mechanisms leading to their development represents a great challenge to improve bone health.
Brunetti, Giacomina +3 more
core +6 more sources
Role of irisin in bone diseases. [PDF]
Front Endocrinol (Lausanne), 2023 Bone diseases are common among middle-aged and elderly people, and harm to activities of daily living (ADL) and quality of life (QOL) for patients. It is crucial to search for key regulatory factors associated with the development of bone diseases and ...
Zhao R +5 more
europepmc +2 more sources
Targeting strategies for bone diseases: signaling pathways and clinical studies
Signal Transduction and Targeted Therapy, 2023 Since the proposal of Paul Ehrlich’s magic bullet concept over 100 years ago, tremendous advances have occurred in targeted therapy. From the initial selective antibody, antitoxin to targeted drug delivery that emerged in the past decades, more precise ...
Hao Xu +8 more
semanticscholar +1 more source
Layered Double Hydroxides: A Novel Promising 2D Nanomaterial for Bone Diseases Treatment
Advancement of science, 2023 Bone diseases including bone defects, bone infections, osteoarthritis, and bone tumors seriously affect life quality of the patient and bring serious economic burdens to social health management, for which the current clinical treatments bear ...
Yixi Bian +7 more
semanticscholar +1 more source
Gut Microbiota and Bone Diseases: A Growing Partnership
Frontiers in Microbiology, 2022 Gut microbiota is key to human health and disease. Convincing studies have demonstrated that dysbiosis in the commensal gut microbiota is associated with intestinal and extra-intestinal diseases.
Yu Chen +5 more
semanticscholar +1 more source
Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases
International Journal of Molecular Sciences, 2022 Bone metabolism consists of a balance between bone formation and bone resorption, which is mediated by osteoblast and osteoclast activity, respectively.
L. Otòn-Gonzalez +9 more
semanticscholar +1 more source
Secondary Osteoporosis and Metabolic Bone Diseases
Journal of Clinical Medicine, 2022 Fragility fracture is a worldwide problem and a main cause of disability and impaired quality of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or quality.
M. Sobh +7 more
semanticscholar +1 more source
Hereditary Metabolic Bone Diseases: A Review of Pathogenesis, Diagnosis and Management
Genes, 2022 Hereditary metabolic bone diseases are characterized by genetic abnormalities in skeletal homeostasis and encompass one of the most diverse groups among rare diseases.
N. Charoenngam +3 more
semanticscholar +1 more source
Research Progress of Exosomes in Bone Diseases: Mechanism, Diagnosis and Therapy
Frontiers in Bioengineering and Biotechnology, 2022 Graphical Abstract With the global escalation of the aging process, the number of patients with bone diseases is increasing year by year. Currently, there are limited effective treatments for bone diseases.
F. Meng +5 more
semanticscholar +1 more source
Metabolic Bone Diseases and New Drug Developments
Biomolecules & Therapeutics, 2022 Metabolic bone diseases are serious health issues worldwide, since several million individuals over the age of 50 are at risk of bone damage and should be worried about their bone health. One in every two women and one in every four men will break a bone
V. Natesan, Sung-jin Kim
semanticscholar +1 more source