Results 21 to 30 of about 1,337,429 (212)

Influence of cytochrome P450 and glutathione S transferase polymorphisms on response to nilotinib therapy among chronic myeloidleukemia patients from Pakistan

open access: yesBMC Cancer, 2022
Background Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens.
Samina Naz Mukry   +3 more
doaj   +1 more source

Effect of BMI on outcomes of surgical treatment for tibial plateau fractures: A comparative retrospective case series study

open access: yesChinese Journal of Traumatology, 2018
Purpose: Tibia plateau fracture (TPF) treatment aims at achieving a stable, aligned, mobile, painless knee and preventing post-traumatic osteoarthritis. To achieve this goal, surgeons consider criteria such as patients' characteristics, severity, risk of
Yaşar Mahsut Dinçel   +5 more
doaj   +1 more source

Measurement of abnormal bone composition in vivo using noninvasive Raman spectroscopy [PDF]

open access: yes, 2014
X-ray-based diagnostic techniques, which are by far the most widely used for diagnosing bone disorders and diseases, are largely blind to the protein component of bone.
Birch, Helen   +8 more
core   +1 more source

Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan

open access: yesBMC Infectious Diseases, 2021
Background Convalescent plasma(CP) was utilized as potential therapy during COVID-19 pandemic in Pakistan. The study aimed at appraisal of CP transfusion safety and usefulness in COVID pneumonia.
Tehmina Nafees Sonia Khan   +15 more
doaj   +1 more source

Sequencing of SARS-CoV-2 in local transmission cases through Oxford Nanopore MinION platform from Karachi Pakistan

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: The first case of severe acute respiratory syndrome 2 (SARS-CoV-2) was imported to Pakistan in February 2020, since then 8,260 deaths have been witnessed.
Samina Naz Mukry   +6 more
doaj   +1 more source

The Assessment of the Osteoporosis Self-Assessment Tool for Asians and Calcaneal Quantitative Ultrasound in Identifying Osteoporotic Fractures and Falls Among Chinese People

open access: yesFrontiers in Endocrinology, 2021
The lack of DXA has made the diagnosis and treatment of osteoporosis extremely difficult in the vast rural areas of China, which has the largest population with high risks of osteoporosis.
Chao Gao   +4 more
doaj   +1 more source

Atypically localized glomus tumor causing anterior interosseous nerve syndrome: A case report

open access: yesActa Orthopaedica et Traumatologica Turcica, 2017
This article presents a 48-year-old male patient who presented with pain in the left forearm and weakness and clumsiness in the left hand of 6 months' duration. Flexor motor strength loss of the thumb and the index finger was present and neurophysiologic
Yunus Emre Akman   +3 more
doaj   +1 more source

Mechanisms underlying bone loss associated with gut inflammation [PDF]

open access: yes, 2019
Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
core   +2 more sources

The Effects of Alpha Interferon on the Development of Autoimmune Thyroiditis in the NOD H2h4 Mouse

open access: yesClinical and Developmental Immunology, 2003
Alpha interferon (αIFN) therapy is known to induce thyroid autoimmunity in up to 40% of patients. The mechanism is unknown, but Th1 switching has been hypothesized.
Yael Oppenheim   +6 more
doaj   +1 more source

Role of SPARC in Bone Remodeling and Cancer‐Related Bone Metastasis [PDF]

open access: yes, 2013
There is a growing socioeconomic recognition that clinical bone diseases such as bone infections, bone tumors and osteoporotic bone loss mainly associated with ageing, are major issues in today0s society.
Brekken, Rolf A.   +3 more
core   +1 more source

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