Results 21 to 30 of about 12,008,318 (406)
Long Noncoding RNA GAS5: A New Factor Involved in Bone Diseases
Frontiers in Cell and Developmental Biology, 2022 Long noncoding RNAs (lncRNAs), as an important type of RNA encoded in the human transcriptome, have shown to regulate different genomic processes in human cells, altering cell type and function.
Zimo Zhou +5 more
semanticscholar +1 more source
Exosome: Function and Application in Inflammatory Bone Diseases
Oxidative Medicine and Cellular Longevity, 2021 In the skeletal system, inflammation is closely associated with many skeletal disorders, including periprosthetic osteolysis (bone loss around orthopedic implants), osteoporosis, and rheumatoid arthritis.
Yingkun Hu +5 more
semanticscholar +1 more source
The Emerging Role of MicroRNAs in Bone Diseases and Their Therapeutic Potential
Molecules, 2021 MicroRNAs (miRNAs) are a class of small (20–24 nucleotides), highly conserved, non-coding RNA molecules whose main function is the post-transcriptional regulation of gene expression through sequence-specific manners, such as mRNA degradation or ...
Luis Alberto Bravo Vázquez +7 more
semanticscholar +1 more source
Osteopontin in Bone Metabolism and Bone Diseases
Medical Science Monitor, 2020 Osteopontin (OPN), a secreted phosphoprotein, is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of cell matrix proteins and participates in many biological activities. Studies have shown that OPN plays a role in bone
Jinyan Si +5 more
semanticscholar +1 more source
International Journal of Endocrinology, 2020 Purpose. GWAS has successfully located and analyzed the pathogenic genes of osteoporosis. Genetic studies have found that heritability of BMD is 50%–85% while the other half is caused by hip geometric parameters and tissue horizontal characteristics ...
Weiwei Hu +8 more
doaj +1 more source
Bone mechanical properties in healthy and diseased states [PDF]
, 2018 The mechanical properties of bone are fundamental to the ability of our skeletons to support movement and to provide protection to our vital organs.
Hussein, Amira I. +2 more
core +1 more source
Hyperparathyroid bone disease [PDF]
Clinical Kidney Journal, 2013 A 52-year-old haemodialysis patient developed normochromic normocytic anaemia requiring weekly blood transfusions. He was resistant to high-dose epoetin alfa and intravenous iron therapy. A blood film examination revealed tear-drop poikilocytes. Serum B12, red cell folate, iron studies, serum protein electrophoresis, serum-free light-chain assay and ...
Nigam, Amit, Kan, George, Morris, Edward
openaire +2 more sources
Swiss Medical Weekly, 2018 In 2008, the Centre Hospitalier Universitaire Vaudois (CHUV, Lausanne, Switzerland) initiated a Fracture Liaison Service (FLS). All patients hospitalised for a low trauma fracture are identified by the FLS.
Bérengère Aubry-Rozier +7 more
doaj +1 more source
Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age [PDF]
, 2018 Cortical bone is permeated by a system of pores, occupied by the blood supply and osteocytes. With ageing, bone mass reduction and disruption of the microstructure are associated with reduced vascular supply.
A Goring +10 more
core +5 more sources
Cancer Reports, 2022 Background Myelodysplastic syndromes (MDS) are heterogeneous group of haematopoietic stem cell disorders and have variable reduction in the production of red cells, platelets and mature granulocytes.
Nida Anwar +5 more
doaj +1 more source