Results 31 to 40 of about 12,008,318 (406)

Clinical Characteristics of Primary Hyperparathyroidism: 15-Year Experience of 457 Patients in a Single Center in China

open access: yesFrontiers in Endocrinology, 2021
ObjectivePrimary hyperparathyroidism (PHPT) is a common endocrine disorder of calcium metabolism. However, data concerning a large cohort of PHPT patients in the Chinese population are scarce.
Xiaoyun Lin   +3 more
doaj   +1 more source

Zinc Homeostasis in Bone: Zinc Transporters and Bone Diseases

open access: yesInternational Journal of Molecular Sciences, 2020
Zinc is an essential micronutrient that plays critical roles in numerous physiological processes, including bone homeostasis. The majority of zinc in the human body is stored in bone. Zinc is not only a component of bone but also an essential cofactor of
Tongling Huang, G. Yan, Min Guan
semanticscholar   +1 more source

Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis

open access: yesPharmaceutics, 2020
Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major issue for modern societies as a consequence of their progressive ageing.
M. Gisbert-Garzarán   +2 more
semanticscholar   +1 more source

Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]

open access: yes, 2020
Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina   +10 more
core   +1 more source

Influence of cytochrome P450 and glutathione S transferase polymorphisms on response to nilotinib therapy among chronic myeloidleukemia patients from Pakistan

open access: yesBMC Cancer, 2022
Background Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens.
Samina Naz Mukry   +3 more
doaj   +1 more source

Measurement of abnormal bone composition in vivo using noninvasive Raman spectroscopy [PDF]

open access: yes, 2014
X-ray-based diagnostic techniques, which are by far the most widely used for diagnosing bone disorders and diseases, are largely blind to the protein component of bone.
Birch, Helen   +8 more
core   +1 more source

Bone Diseases: Current Approach and Future Perspectives in Drug Delivery Systems for Bone Targeted Therapeutics

open access: yesNanomaterials, 2020
Bone diseases include a wide group of skeletal-related disorders that cause mobility limitations and mortality. In some cases, e.g., in osteosarcoma (OS) and metastatic bone cancer, current treatments are not fully effective, mainly due to low patient ...
Giulia Chindamo   +5 more
semanticscholar   +1 more source

Effect of BMI on outcomes of surgical treatment for tibial plateau fractures: A comparative retrospective case series study

open access: yesChinese Journal of Traumatology, 2018
Purpose: Tibia plateau fracture (TPF) treatment aims at achieving a stable, aligned, mobile, painless knee and preventing post-traumatic osteoarthritis. To achieve this goal, surgeons consider criteria such as patients' characteristics, severity, risk of
Yaşar Mahsut Dinçel   +5 more
doaj   +1 more source

Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan

open access: yesBMC Infectious Diseases, 2021
Background Convalescent plasma(CP) was utilized as potential therapy during COVID-19 pandemic in Pakistan. The study aimed at appraisal of CP transfusion safety and usefulness in COVID pneumonia.
Tehmina Nafees Sonia Khan   +15 more
doaj   +1 more source

Sequencing of SARS-CoV-2 in local transmission cases through Oxford Nanopore MinION platform from Karachi Pakistan

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: The first case of severe acute respiratory syndrome 2 (SARS-CoV-2) was imported to Pakistan in February 2020, since then 8,260 deaths have been witnessed.
Samina Naz Mukry   +6 more
doaj   +1 more source

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