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Frontiers in Endocrinology, 2021 The lack of DXA has made the diagnosis and treatment of osteoporosis extremely difficult in the vast rural areas of China, which has the largest population with high risks of osteoporosis.
Chao Gao +4 more
doaj +1 more source
The Role of NLRP3 Inflammasome Activities in Bone Diseases and Vascular Calcification
Inflammation, 2020 Continuous stimulation of inflammation is harmful to tissues of an organism. Inflammatory mediators not only have an effect on metabolic and inflammatory bone diseases but also have an adverse effect on certain genetic and periodontal diseases associated
Chenyang Yu +3 more
semanticscholar +1 more source
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
, 2006 BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources
Role of SPARC in Bone Remodeling and Cancer‐Related Bone Metastasis [PDF]
, 2013 There is a growing socioeconomic recognition that clinical bone diseases such as bone infections, bone tumors and osteoporotic bone loss mainly associated with ageing, are major issues in today0s society.
Brekken, Rolf A. +3 more
core +1 more source
Osteocyte apoptosis: the roles and key molecular mechanisms in resorption-related bone diseases
Cell Death and Disease, 2020 Vital osteocytes have been well known to function as an important orchestrator in the preservation of robustness and fidelity of the bone remodeling process.
J. Ru, Yan-fen Wang
semanticscholar +1 more source
Mechanisms underlying bone loss associated with gut inflammation [PDF]
, 2019 Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
core +2 more sources
Long non-coding RNA MEG3 is involved in osteogenic differentiation and bone diseases (Review)
Biomedical Reports, 2020 Osteogenic differentiation originating from mesenchymal stem cells (MSCs) requires tight co-ordination of transcriptional factors, signaling pathways and biomechanical cues.
Hong Sun +7 more
semanticscholar +1 more source
Atypically localized glomus tumor causing anterior interosseous nerve syndrome: A case report
Acta Orthopaedica et Traumatologica Turcica, 2017 This article presents a 48-year-old male patient who presented with pain in the left forearm and weakness and clumsiness in the left hand of 6 months' duration. Flexor motor strength loss of the thumb and the index finger was present and neurophysiologic
Yunus Emre Akman +3 more
doaj +1 more source
RAGs and Regulation of Autoantibodies [PDF]
, 2004 Autoreactive antibodies are etiologic agents in a number of autoimmune diseases. Like all other antibodies these antibodies are produced in developing B cells by V(D)J recombination in the bone marrow.
Casellas, Rafael +4 more
core +1 more source
Providing high-quality care remotely to patients with rare bone diseases during COVID-19 pandemic
Orphanet Journal of Rare Diseases, 2020 During the COVID-19 outbreak, the European Reference Network on Rare Bone Diseases (ERN BOND) coordination team and Italian rare bone diseases healthcare professionals created the “COVID-19 Helpline for Rare Bone Diseases” in an attempt to provide high ...
E. Brizola +25 more
semanticscholar +1 more source