Results 51 to 60 of about 1,337,429 (212)

Correlation Between Low Bone Density and Disease Activity in Patients with Ulcerative Colitis [PDF]

, 2015
BACKGROUND Different clinical and epidemiological studies using dual-energy X-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.
Aghaei, M., Amiriani, T., Besharat, M., Besharat, S., Faghani, M., Joshaghani, H., Mirkarimi, H.S., Pourramezan, Z., Roshandel, G.   +8 more
core  

Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors. [PDF]

, 2010
IntroductionThe interaction between the immune and skeletal systems is evidenced by the bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we describe a new mechanism by which the immune cytokine IL-17A directly affects
Adamopoulos, Iannis E, Blumenschein, Wendy, Bowman, Edward P, Chao, Cheng-Chi, Geissler, Richard, Iwakura, Yoichiro, Laface, Drake, McClanahan, Terrill   +7 more
core   +1 more source

The dental management of patients at risk of medication-related osteonecrosis of the jaw: New paradigm of primary prevention [PDF]

, 2018
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is a potentially painful and debilitating condition that can considerably affect the quality of life of patients ...
Bedogni, Alberto, Campisi, Giuseppina, Di Fede, Olga, Fusco, Vittorio, Lo Muzio, Lorenzo, Mauceri, Rodolfo, Panzarella, Vera, Sipmo Onj Board, Null   +7 more
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Muscle and bone characteristics of a Chinese family with spinal muscular atrophy, lower extremity predominant 1 (SMALED1) caused by a novel missense DYNC1H1 mutation

BMC Medical Genomics, 2023
Background Spinal muscular atrophy, lower extremity predominant (SMALED) is a type of non-5q spinal muscular atrophy characterised by weakness and atrophy of lower limb muscles without sensory abnormalities.
Yazhao Mei, Yunyi Jiang, Zhenlin Zhang, Hao Zhang   +3 more
doaj   +1 more source

Myeloma bone disease

Hematology, 2005
Bone destruction is a hallmark of multiple myeloma, and recent studies demonstrated a strong interdependence between tumor progression and bone resorption. Increased bone resorption as a major characteristic of multiple myeloma is caused by osteoclast activation and osteoblast inhibition (uncoupling).
openaire   +2 more sources

Adynamic bone disease--bone and beyond [PDF]

Clinical Kidney Journal, 2008
Disturbances of bone and mineral metabolism are a hallmark of chronic kidney disease (CKD). Renal osteodystrophy (ROD) is the traditional term for bone lesions in conjunction with CKD and is now considered a part of the ‘chronic kidney disease—mineral and bone disorder’ (CKD-MBD) [1].
Brandenburg, Vincent M., Floege, Jürgen
openaire   +2 more sources

Endothelial Progenitor Cells: Relevant Players in the Vasculopathy and Lung Fibrosis Associated with the Presence of Interstitial Lung Disease in Systemic Sclerosis Patients

Biomedicines, 2021
Endothelial progenitor cells (EPC), which are key effectors in the physiologic vascular network, have been described as relevant players in autoimmune diseases.
Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Raquel Pérez-Fernández, Diana Prieto-Peña, Virginia Portilla, Ricardo Blanco, Alfonso Corrales, Oreste Gualillo, José M. Cifrián, Raquel López-Mejías, Miguel A. González-Gay   +15 more
doaj   +1 more source

A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]

, 2015
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans, Dehoorne, Jo, Van Biervliet, Stephanie, van Ommen, Christi, Van Winckel, Myriam, Vande Velde, Saskia   +5 more
core  

Switch to maraviroc with darunavir/r, both QD, in patients with suppressed HIV-1 was well tolerated but virologically inferior to standard antiretroviral therapy: 48-Week results of a randomized trial [PDF]

, 2017
Objectives Primary study outcome was absence of treatment failure (virological failure, VF, or treatment interruption) per protocol at week 48.
Antinori, Andrea, Biagio, Antonio Di, Canovari, Benedetta, Colafigli, Manuela, Colangeli, Vincenzo, De Luca, Andrea, D’Arminio Monforte, Antonella, D’Avino, Alessandro, Fantauzzi, Alessandra, Francisci, Daniela, Gagliardini, Roberta, Ghisetti, Valeria, Giambenedetto, Simona Di, Grima, Pierfrancesco, Lamonica, Silvia, Latini, Alessandra, Lisi, Lucia, Mastroianni, Claudio, Meini, Genny, Micheli, Valeria, Navarra, Pierluigi, Orofino, Giancarlo, Re, Maria Carla, Rossetti, Barbara, Rusconi, Stefano, Sterrantino, Gaetana, Trezzi, Michele, Vignale, Francesca, Vullo, Vincenzo, Zazzi, Maurizio   +29 more
core   +5 more sources

Metabolomics study of osteopetrosis caused by CLCN7 mutation reveals novel pathway and potential biomarkers

Frontiers in Endocrinology
ObjectiveCLCN7 mutation caused abnormal osteoclasts, resulting in osteopetrosis. Depending on the type of mutation, CLCN7 mutations can lead to severe or relatively benign forms of osteopetrosis.
Xi Chen, Ziyuan Wang, Wenzhen Fu, Zhe Wei, Jiemei Gu, Chun Wang, Zhenlin Zhang, Zhenlin Zhang, Xiangtian Yu, Weiwei Hu   +9 more
doaj   +1 more source