Results 51 to 60 of about 12,008,318 (406)
The Effects of Alpha Interferon on the Development of Autoimmune Thyroiditis in the NOD H2h4 Mouse
Clinical and Developmental Immunology, 2003 Alpha interferon (αIFN) therapy is known to induce thyroid autoimmunity in up to 40% of patients. The mechanism is unknown, but Th1 switching has been hypothesized.
Yael Oppenheim +6 more
doaj +1 more source
Molecular Genetics & Genomic Medicine, 2022 Background To investigate the clinical characteristics and molecular diagnosis of Camurati‐Engelmann disease (CAEND) in Chinese individuals. Methods We recruited six patients aged 14 to 45 years in three unrelated families with CAEND, including five ...
Xiao‐Hui Tao +7 more
doaj +1 more source
RAGE Signaling in Skeletal Biology [PDF]
, 2019 PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
core +2 more sources
Anti-Sclerostin Antibodies in Osteoporosis and Other Bone Diseases
Journal of Clinical Medicine, 2020 The Wnt pathway is a key element of bone remodeling; its activation stimulates bone formation and inhibits bone resorption. The discovery of sclerostin, a natural antagonist of the Wnt pathway, promoted the development of romosozumab, a human monoclonal ...
S. Fabre +2 more
semanticscholar +1 more source
BMJ Case Reports, 2015 Osteopoikilosis, a benign autosomal dominant bone disorder, is an unusual condition that can often be misdiagnosed as a sinister primary bone anomaly or as metastatic bony lesions. We report a case of osteopoikilosis in a 29-year-old Indian man. A 29-year-old unmarried man, born of non-consanguineous parents, presented with a history of low back pain ...
Riddhi, Dasgupta, Nihal, Thomas
openaire +2 more sources
The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases
Frontiers in Endocrinology, 2020 Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in humans. In the past osteocytes have been regarded as vestigial cells in bone, since they are buried inside the tough bone matrix.
J. Pathak +2 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Bone is a mineralized and elastic connective tissue that provides fundamental functions in the human body, including mechanical support to the muscles and joints, protection of vital organs and storage of minerals.
M. Terkawi +5 more
semanticscholar +1 more source
Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society [PDF]
, 2020 The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation ...
et al, +2 more
core +1 more source
Short- and long-term effects of a multi-component physical activity intervention in primary school [PDF]
, 2012 There is compelling evidence that physical activity has numerous health benefits during childhood and adolescence. Insufficient levels of physical activity on the other hand can consequently affect cardiovascular and bone health, which may result in ...
Meyer, Ursina
core +1 more source
Bone Diseases in Patients with Chronic Liver Disease
International Journal of Molecular Sciences, 2019 Osteoporosis is a frequently observed complication in patients with chronic liver disease, particularly liver cirrhosis and cholestatic liver diseases. In addition, osteoporosis is critical in patients receiving a liver transplant.
Hae Min Jeong, D. J. Kim
semanticscholar +1 more source