Results 91 to 100 of about 1,552,377 (310)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

3′-Sialyllactose alleviates bone loss by regulating bone homeostasis

Communications Biology
Osteoporosis is a common skeletal disease that results in an increased risk of fractures. However, there is no definitive cure, warranting the development of potential therapeutic agents.
Ahreum Baek, Dawoon Baek, Yoonhee Cho, Seongmoon Jo, Jinyoung Kim, Yoontaik Hong, Seunghee Cho, Sung Hoon Kim, Sung-Rae Cho   +8 more
doaj   +1 more source

Combined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition [PDF]

, 2017
The endocannabinoid system plays a role in regulating bone mass and bone cell activity and inactivation of the type 1 (Cnr1) or type 2 (Cnr2) cannabinoid receptors influences peak bone mass and age-related bone loss.
Agudo, Aitken, Armour, Bab, Burton, Campbell, Champigny, Colombo, Cota, Demuth, Erben, Gloeckner, Greenspan, Idris, Idris, Idris, Idris, Idris, Idris, Jepsen, Kirkham, Ledent, Marsicano, Matias, Matsuda, Mechoulam, Munro, Ntambi, Ofek, Ofek, Pacifici, Pertwee, Raisz, Richelson, Rossi, Sophocleous, Sophocleous, Sophocleous, Sophocleous, Sophocleous, Tam, Tam, Taylor, Whyte   +43 more
core   +2 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Principal components analysis on audiograms from a hearing aid clinic [PDF]

, 2010
In this study we describe a Principal Components Analysis (PCA) of 11,462 audiograms recorded at the hearing aid clinic at James Cook University Hospital in Middlesbrough between 1992 and 2001.
Anwar, Naveed, Oakes, Michael
core  

Radiological assessment of peri-implant bone loss: a 12-month retrospective study [PDF]

, 2011
Introduction: Following dental implant loading, marginal bone loss after one year must be evaluated to check correct maintenance of the bone levels. Objectives: To assess implant treatment success and quantify marginal bone loss 6 and 12 months after ...
Ata-Ali Mahmud, Francisco Javier, Conejero, J., Flichy Fernández, Antonio, Palma Carrió, Cristina, Peñarrocha Diago, María, Peñarrocha Oltra, David   +5 more
core   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Can medio-lateral baseplate position and load sharing induce asymptomatic local bone resorption of the proximal tibia? : a finite element study [PDF]

, 2009
Background Asymptomatic local bone resorption of the tibia under the baseplate can occasionally be observed after total knee arthroplasty (TKA). Its occurrence is not well documented, and so far no explanation is available.
Innocenti, Bernardo, Truyens, Evelyn, Labey, Luc, Wong, Pius, Victor, Jan, Bellemans, Johan   +5 more
core   +3 more sources

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source

From Mechanical Machining Technology: A New Solution That Integrates Blades to the Implant to Control the Stress to the Peri-Implant Cortical Bone

Bioengineering
Background: To prevent excessive compression of the cortical layer, which can lead to marginal bone loss, various companies have introduced specialized drills.
Mauro Ferri, Marco Guzzo, Hiroyuki Omori, Yuma Hazama, Nicodemo Vittorio Masotta, Daniele Botticelli   +5 more
doaj   +1 more source