Results 101 to 110 of about 4,190,471 (295)

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Biologically rational ways of bone mass loss prophylaxis and treatment

Travmatologiâ i Ortopediâ Rossii, 2016
Aim. Based on own and literature date to define biologically rational elements of complex approach to bone mass loss prophylaxis and treatment. Nowadays there are two points of view regarding bone mass loss prophylaxis and treatment.
A. S. Avrunin, A. A. Doktorov
doaj  

Medicines and Bone Loss [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2013
Jens, Bollerslev, Steven T, Harris, Benjamin Z, Leder   +2 more
openaire   +2 more sources

Predictive Value of Osteoporosis Risk Factors for Bone Loss

, 2003
Osteoporosis is a serious and costly public health problem. It is important that subjects with risk for bone loss determine in a way that is economical and practical.
Merih Eryavuz Sarıdoğan, İlhan Karacan, Şafak S. Karamehmetoğlu, İmdat Özkul   +3 more
core  

Polymorphisms in the macrophage migration inhibitory factor gene and bone loss in postmenopausal women. [PDF]

, 2010
Osteoporosis is a severe condition in postmenopausal women and a common cause of fracture. Osteoporosis is a complex disease with a strong genetic impact, but susceptibility is determined by many genes with modest effects and environmental factors.
Paul Gerdhem, Richard Bucala, Åkesson, Kristina, Kaisa K. Ivaska, Ivaska, Kaisa K, Kuchel, G, Lerner, Ulf H,, Ivaska, Kaisa, Ivaska, KK, Ulf H. Lerner, Kenny, Anne, George Kuchel, Maria Swanberg, Gerdhem, Paul, Bucala, R, Kenny, A, Bucala, Richard, Anne Kenny, McGuigan, F, Fiona McGuigan, Kristina Åkesson, McGuigan, Fiona, Akesson, K, Lerner, Ulf H, Swanberg, M, Gerdhem, P,, Lerner, UH, Swanberg, Maria, Kuchel, George   +28 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Effect of RANKL/OPG Balance on Reducing Implant Complications

Journal of Functional Biomaterials, 2017
Despite the phenomenal success of implants particularly in the realms of dentistry and orthopaedics, there are still challenges to overcome. The failure of implants resulting from infection, prosthetic loosening, and non-union continue to be the most ...
Elizabeth R. Kapasa, Peter V. Giannoudis, Xiaodong Jia, Paul V. Hatton, Xuebin B. Yang   +4 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation [PDF]

, 2010
Background: Clock genes and their protein products regulate circadian rhythms in mammals but have also been implicated in various physiological processes, including bone formation.
Maronde, E. (Erik), Amling, Michael, Schinke, T. (Thorsten), Schilling, A.F. (Arndt), Schinke Thorsten, Seitz, S. (Sebastian), Albrecht Urs, Arndt F Schilling, Amling Michael, Urs Albrecht, Maronde, Erik, Schmutz, I. (Isabelle), Maronde Erik, Isabelle Schmutz, Horst, Gijsbertus van der, Thorsten Schinke, Schmutz Isabelle, Seitz, Sebastian, Schilling, Arndt F., Schilling Arndt F., Arndt F. Schilling, Seitz Sebastian, Schilling, Arndt, Sebastian Seitz, Schinke, Thorsten, Albrecht, U. (Urs), Schmutz, Isabelle, Amling, M. (Michael), Erik Maronde, Albrecht, Urs, Horst, G.T.J. (Gijsbertus) van der, Gijsbertus van der Horst, Michael Amling, van der Horst Gijsbertus   +33 more
core   +1 more source