Results 71 to 80 of about 23,719 (219)

Does Needle Design Affect the Regenerative Potential of Bone Marrow Aspirate? An In Vitro Study

Life, 2021
While autologous bone is still the gold standard for treatment of bone defects, its availability is limited. Sufficient numbers of mesenchymal stroma cells (MSC) may be an alternative.
Nadia Feddahi, Monika Herten, Tjark Tassemeier, Heike Rekasi, Alexander Hackel, Marcel Haversath, Marcus Jäger   +6 more
doaj   +1 more source

Different methods of bone marrow harvesting influence cell characteristics and purity, affecting clinical outcomes

JVS - Vascular Science, 2023
Background: Bone marrow (BM)-derived stem cells were implanted to induce angiogenesis in patients with no-option critical limb-threatening ischemia. Considering the potential for this therapy, conflicting results related to BM harvesting methods have ...
Eugenio Caradonna, MD, Elisabetta Mormone, PhD, Enrico Maria Centritto, MD, Andrea Mazzanti, MD, PhD, Stefano Papini, MD, Mara Fanelli, PhD, Lella Petrella, PhD, Arnolfo Petruzziello, MD, Michele Angelo Farina, MD, Eleonora Farina, MD, Bruno Amato, MD, Carlo Maria De Filippo, MD, Emilio Vanoli, MD   +12 more
doaj   +1 more source

Bone-marrow-based augmentation in rotator cuff repair—from microfracture to bone marrow aspirate concentrate [PDF]

Obere Extremität
AbstractRotator cuff tears are a major cause of shoulder dysfunction, and relatively high rates of rotator cuff re-tear persist despite surgical advancements, particularly in patients with poor biological healing potential. Bone-marrow-based augmentation techniques, specifically bone marrow stimulation (BMS) and bone marrow aspirate concentrate (BMAC),
Marco-Christopher Rupp, Zeeshan A. Khan, Juan Villarreal, Nikhil Verma, Jorge Chahla   +4 more
openaire   +2 more sources

Matrix-Associated Chondroplasty: A Novel Platelet-Rich Plasma and Concentrated Nucleated Bone Marrow Cell–Enhanced Cartilage Restoration Technique

Arthroscopy Techniques, 2014
Bone marrow stimulation techniques such as microfracture for the treatment of articular cartilage defects so far solely reproduce mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm.
Matthias R. Steinwachs, M.D., Bernhard Waibl, M.D., Stephanie Wopperer, M.D., Marcus Mumme, M.D.   +3 more
doaj   +1 more source

Transtendinous Rotator Cuff Tear Repair with Bone Marrow Aspirate Concentrate Dermal Allograft Augmentation

Arthroscopy Techniques, 2021
Rotator cuff tears involving the musculotendinous junction with a significant amount of tendon still attached to the footprint laterally represent a challenging scenario for shoulder arthroscopists.
Peter Neff, M.D., Don B. Franklin, III, M.D., Daniel L. Jones, M.D., Sarah D. Lang, M.Ed., A.T.C., O.T.C., Haley R. Nadone, M.S., Brian B. Gilmer, M.D., Dan Guttmann, M.D.   +6 more
doaj   +1 more source

Bridging the gap: Bone marrow aspiration concentrate reduces autologous bone grafting in osseous defects [PDF]

Journal of Orthopaedic Research, 2010
AbstractAlthough autologous bone grafting represents an effective tool to induce osteogenic regeneration in local bone defects or pseudarthroses, it is associated with significant donor site morbidity and limited by the amount available for grafting. We investigate the potency of bone marrow aspiration concentrate (BMAC) to augment bone grafting and ...
Jäger, M., Herten, Monika, Fochtmann, U., Fischer, J., Hernigou, P., Zilkens, C., Hendrich, C., Krauspe, R.   +7 more
openaire   +3 more sources

Editorial Commentary: Bone Marrow Aspirate Concentrate: Time to Harvest Locally? [PDF]

Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2020
Cell therapies hold great promise as primary and adjuvant treatments for a range of musculoskeletal conditions. Bone marrow harvested from the iliac crest represents the gold-standard source of progenitor cells with a recognized ability to release trophic factors, modulate local immune environments, and differentiate into multiple musculoskeletal cell ...
Robert F, LaPrade, Iain R, Murray
openaire   +2 more sources

Dysfunctional stem and progenitor cells impair fracture healing with age [PDF]

, 2019
Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new vasculature that supplies ...
Clauss, Matthias, Fennimore, Alanna, Gunderson, Zachary J., Kacena, Melissa A., Karnik, Sonali, Li, Jiliang, Loghmani, M. Terry, Low, Philip S., Lowery, Jonathan W., McKinley, Todd O., Nielsen, Jeffery J., Promer, Hunter J., Wagner, Diane R.   +12 more
core   +1 more source

Factors Influencing the yield of progenitor cells in bone marrow aspiration concentrate—A retrospective analysis of 58 patients [PDF]

, 2023
This study aims to identify the role of subjective factors (age, sex, and comorbidities) and procedure-specific factors (aspiration volume) in influencing the yield of progenitor cells in bone marrow aspiration concentrate (BMAC) harvested from the iliac
Aditya Narula, Ashim Gupta, Avinash Gandi, Madhan Jeyaraman, Manish Khanna, Nicola Maffulli, Sathish Muthu, V. R. Ravi   +7 more
core   +1 more source

Dry Arthroscopic Single-Stage Cartilage Repair of the Knee Using a Hyaluronic Acid-Based Scaffold With Activated Bone Marrow-Derived Mesenchymal Stem Cells

Arthroscopy Techniques, 2016
Cartilage lesions of the knee are a frequent finding; however, treatment options that are capable of restoring hyaline-like tissue are not routinely used. Cell-based technology such as autologous chondrocyte implantation may in some cases provide durable
Graeme P. Whyte, M.D., M.Sc., F.R.C.S.C., Alberto Gobbi, M.D., Boguslaw Sadlik, M.D., Ph.D.   +2 more
doaj   +1 more source