Results 81 to 90 of about 6,967 (325)

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Mesenchymal Stem Cell Approach for Maxillary Sinus Grafting [PDF]

, 2014
Autogenous bone has long been a gold standard grafting material for bone defects. It possesses osteogenic, osteoinductive and osteoconductive properties ideal for bone healing.
Cheung, LK, Sununliganon, L
core  

Dysfunctional stem and progenitor cells impair fracture healing with age [PDF]

, 2019
Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new vasculature that supplies ...
Clauss, Matthias, Fennimore, Alanna, Gunderson, Zachary J., Kacena, Melissa A., Karnik, Sonali, Li, Jiliang, Loghmani, M. Terry, Low, Philip S., Lowery, Jonathan W., McKinley, Todd O., Nielsen, Jeffery J., Promer, Hunter J., Wagner, Diane R.   +12 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

Advanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng, Isaak Decoene, Hanna Svitina, Ioannis Papantoniou   +3 more
wiley   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review. [PDF]

, 2017
BACKGROUND: The management of articular cartilage defects presents many clinical challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation techniques, such as microfracture, are the most frequently used method in clinical ...
A Badri, A Bedi, A Gigante, A Gobbi, A Gobbi, A Heymer, A Ivkovic, A Liberati, A Ma, A Rey-Rico, A Shafiee, A Siclari, A Steinert, A Vega, A Yokoyama, AA Hegewald, AA Shetty, AA Worster, AAM Dhollander, AJ Neumann, AM Bhosale, AM Haleem, AM Lubis, AN Mokbel, Andy Goldberg, AS Levy, AT Mehlhorn, B Dozin, B Grigolo, B Hu, B Marquass, B Marquass, B Qi, B Zhang, BS Bal, BT Estes, C An, C Kasemkijwattana, C Millan, C Miyamoto, C Perka, C Spadaccio, C-H Chang, C-H Lu, C-H Lu, C-Y Charles Huang, C-YC Huang, CH Jo, CK Abrahamsson, CM Capeci, CSD Lee, CT Buckley, CT Lim, CW McIlwraith, D Enea, D Guenther, D Hannouche, D Murata, D Xue, D-H Kim, DA Grande, DG Jones, DJ Dandy, DJ Ogilvie-Harris, DK Bae, DR Diduch, E Kon, E López-Ruiz, EG Meyer, EG Popa, EJ Caterson, F Caro De, F Davatchi, F Hildner, F Li, F Meng, F Shapiro, F Song, G Bentley, G Bentley, G Feng, G Kamei, G Meachim, G Musumeci, G Wu, G Zhou, G-I Im, G-I Im, GI Im, GR Erickson, H Al Faqeh, H Dashtdar, H Diao, H Fan, H Fan, H Huade Li, H Huang, H Kang, H Koga, H Koga, H Koga, H Nejadnik, H Yan, H-J Kim, HY Nam, I Akgun, I Sekiya, I Sekiya, I-S Yoon, IE Erickson, IE Erickson, Insall JN, J Chung, J Frisch, J Gille, J Kim, J Lam, J Leijten, J Pak, J Sun, J Xie, J-C Lee, J-C Lee, J-C Lee, JA Rand, JB Moseley, JC Babister, JH Cui, JI Huang, JJ Wood, JL Dragoo, JL Dragoo, JM Bert, JM Coburn, JM Murphy, JR Steadman, JS Park, JU Yoo, Julian Soans, K Froelich, K Gelse, K Ishihara, K Masuoka, K Mithoefer, K Mithoefer, K Uematsu, K Ye, K Ye, K Zhang, K-Y Saw, K-Y Saw, K-Y Saw, Katrina Mitchell, KBL Lee, KBL Lee, KEM Benders, KL Wong, L Bartha, L Cui, L Girolamo de, L Gong, L Gossec, L Orozco, L Pilgaard, L Zhang, LA Fortier, LA Solchaga, LF Raheja, LL Johnson, Louise Kim, LX Tay, M Betsch, M Brittberg, M Brittberg, M Caminal, M Espinosa, M Jagielski, M Jung, M Kayakabe, M Kim, M Maumus, M Nawata, M Nishimori, M Pei, M Pei, M Petrou, M Sato, M Spoliti, M Tatebe, M Zengerink, M Zscharnack, MB Eslaminejad, MM Wilke, MQ Wickham, MR Steinwachs, MS Ponticiello, N Takata, N-C Cheng, N-C Cheng, NC Keramaris, NJ Castro, P Angele, P Feczkó, P Giannoni, P Leng, P Pastides, P-F Liu, PD Benya, PH Ousema, PN Dang, Q Zhao, R Buda, R Iwai, R Katayama, R Kuroda, R Mhanna, R Narcisi, R Seda Tigli, RA Magnussen, RA Oldershaw, Razi Zaidi, RB Dzioba, RL Dahlin, RM Coleman, RM Schulz, RR Varshney, S Araki, S Bhumiratana, S Focaroli, S Giannini, S Giannini, S Lee, S Løken, S Nathan, S Portron, S Saha, S Suzuki, S Wakitani, S Wakitani, S Wakitani, S Wakitani, S Zhang, S Zhu, SH Woolf, SP Medvedev, STB Ho, T Deng, T Igarashi, T Kobayashi, T Kusano, T Li, T Matsumoto, T Minas, T Minas, T Nakamura, T Vinardell, T Yoshioka, T Zantop, TD Bornes, TM Liu, TY Hui, W Bartlett, W Wan, W Wang, W-C Chen, W-C Chen, W-K Jeong, WD Bugbee, X Chen, X Ding, X Duan, X Ma, X Shao, X Xie, X Yang, X Zhang, XZ Zhou, Y Han, Y Han, Y Jung, Y Liu, Y Matsusue, Y Mifune, Y Oshima, Y Oshima, Y Oshima, Y Park, Y Qi, Y Qi, Y Sato, Y Wei, Y Wei, Y Wei, Y Wei, Y Zhang, Y-G Koh, YG Koh, YS Kim, Z Gong, Z Huang, Z Li, ZJ Wang   +301 more
core   +3 more sources

Lesser Tarsal Metatarsal Joint Fusion Using Nitinol Staples, Bone Marrow Aspirate Concentrate and a Calcaneal Bone Dowel: A Retrospective Comparative Analysis [PDF]

, 2022
Jared Scott, Jay C. Thompson, Mark J. Johnson, Michael R. Anderson, Bryan J. Hawkins   +4 more
openalex   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Correction to: Osteocondritis dissecans lesions of the knee restored by bone marrow aspirate concentrate: clinical and imaging results in 18 patients [PDF]

, 2023
Matteo Baldassarri, Roberto Buda, Luca Perazzo, Diego Ghinelli, Sarino Ricciardello, Brunella Grigolo, Cesare Faldini   +6 more
openalex   +1 more source