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Frontiers in Immunology, 2022 BackgroundGlucocorticoids (GCs) are often used to treat cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). The effects of GCs on the efficacy of CAR-T cell treatment in relapsed/refractory multiple myeloma
Xue Wang +36 more
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Frontiers in Immunology, 2023 BackgroundChimeric antigen receptor - T (CAR-T) cell therapy has shown remarkable efficacy in patients with relapsed/refractory multiple myeloma (R/R MM).
Yang Liu +57 more
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Frontiers in Immunology, 2022 IntroductionGraft-versus-host disease (GVHD) damages vascular endothelium. Endothelial progenitor cell (EPC) can differentiate to endothelial cell and promote angiogenesis, but its role in endothelial damage in GVHD is unclear.MethodsIn this study, we ...
Weiwei Wang +35 more
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A T Cell View of the Bone Marrow [PDF]
Frontiers in Immunology, 2016 The majority of T cells present in the bone marrow (BM) represent an activated/memory phenotype and most of these, if not all, are circulating T cells. Their lodging in the BM keeps them activated, turning the BM microenvironment into a "memory reservoir." This article will focus on how T cell activation in the BM results in both direct and indirect ...
Ana Carolina Monteiro +7 more
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CCN3 and bone marrow cells [PDF]
Journal of Cell Communication and Signaling, 2009 AbstractCCN3 expression was observed in a broad variety of tissues from the early stage of development. However, a kind of loss of function in mice (CCN3 del VWC domain ‐/‐) demonstrated mild abnormality, which indicates that CCN3 may not be critical for the normal embryogenesis as a single gene.
Akira Yamaguchi +10 more
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Journal of Hematology & Oncology, 2023 B cell maturation antigen (BCMA)-targeted immunotherapy has shown unprecedented results in the treatment of relapsed or refractory (R/R) multiple myeloma (MM).
Jieyun Xia, Zhenyu Li, Kailin Xu
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Schwann Cells of the Bone Marrow [PDF]
Blood, 1970 Abstract Nerves containing numerous Schwann cells can be found in bone marrow with routine histological methods. Thin nerve bundles and single nerve fibers containing Schwann cells can be identified histologically with help of methods which demonstrate nerve fibers and myelin. Smears of marrow stained with the May-Grünwald-Giemsa method
Jerónimo Forteza-Vila, Wenceslao Calvo
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Bone marrow SSEA1+ cells support the myocardium in cardiac pressure overload. [PDF]
PLoS ONE, 2013 Stage specific embryonic antigen 1+ (SSEA1+) cells have been described as the most primitive mesenchymal progenitor cell in the bone marrow. Cardiac injury mobilizes SSEA1+ cells into the peripheral blood but their in vivo function has not been ...
Amanda Finan +5 more
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Induction of VEGF secretion from bone marrow stromal cell line (ST-2) by the dissolution products of mesoporous silica glass particles containing CuO and SrO [PDF]
J. Non-cryst. Solids. 500, 217-224 (2018), 2021 Certain biomaterials are capable of inducing the secretion of Vascular Endothelial Growth Factor (VEGF) from cells exposed to their biochemical influence, which plays a vital role in stimulating angiogenesis. Looking for this capacity, in this study three porous glasses were synthesized and characterized.
arxiv +1 more source
Karyotype of cryopreserved bone marrow cells [PDF]
Brazilian Journal of Medical and Biological Research, 2003 The analysis of chromosomal abnormalities is important for the study of hematological neoplastic disorders since it facilitates classification of the disease. The ability to perform chromosome analysis of cryopreserved malignant marrow or peripheral blast cells is important for retrospective studies.
Chauffaille, Maria de Lourdes Lopes Ferrari UNIFESP +3 more
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